Lower limb monochorea from a globus pallidus infarct

Pandey, Sanjay; Gupta, Swapan

doi:10.1016/j.jocn.2013.10.038

Cited by 4 publications

(1 citation statement)

References 7 publications

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“…A search in PubMed revealed few case reports of strokes presenting with isolated monochorea, none of which were published in emergency medicine journals. Pandey and Gupta describe a similar case to ours of a 47-year-old male with sudden onset choreiform movement of the left lower extremity [1]. This patient also notably exhibited normal strength in the affected extremity.…”

Section: Discussionsupporting

confidence: 74%

Acute Stroke Presenting as Unilateral Lower Extremity Monochorea

O'Donnell¹,

Siddiqui²

2021

Cureus

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Stroke is a common condition that can present with a wide range of signs and symptoms based on the region of the brain experiencing impaired perfusion. As the diagnosis and treatment of acute strokes is frequently initiated in the emergency department (ED), early recognition by emergency providers is essential in providing patients with the best chance of recovery and symptom resolution while attempting to minimize the risk of disability. While lateralizing weakness, numbness, and speech changes are among the most common symptoms of a stroke, in rare cases, patients may present with subtle or atypical symptoms, necessitating a high index of suspicion as well as a thorough history and physical examination. We present a case of acute ischemic stroke presenting with isolated choreiform movement.

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Section: Discussionsupporting

confidence: 74%

Acute Stroke Presenting as Unilateral Lower Extremity Monochorea

O'Donnell¹,

Siddiqui²

2021

Cureus

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Significance of N-isopropyl-[123I] p-iodoamphetamine single-photon emission computed tomography in detection of responsible hypoperfusion in hemichorea

Sehara

Otsuka²,

Kaneko

et al. 2019

Journal of Clinical Neuroscience

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Treatment options for chorea

Bashir

Jankovic

2017

Expert Review of Neurotherapeutics

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Chorea is defined as jerk-like movements that move randomly from one body part to another. It is due to a variety of disorders and although current symptomatic therapy is quite effective there are few etiology- or pathogenesis-targeted therapies. The aim of this review is to summarize our own experience and published evidence in the treatment of chorea. Areas covered: After evaluating current guidelines and clinical practices for chorea of all etiologies, PubMed was searched for the most recent clinical trials and reviews using the term 'chorea' cross referenced with specific drug names. Expert commentary: Inhibitors of presynaptic vesicular monoamine transporter type 2 (VMAT2) that cause striatal dopamine depletion, such as tetrabenazine, deutetrabenazine, and valbenazine, are considered the treatment of choice in patients with chorea. Some clinicians also use dopamine receptor blockers (e.g. antipsychotics) and other drugs, including anti-epileptics and anti-glutamatargics. 'Dopamine stabilizers' such as pridopidine and other experimental drugs are currently being investigated in the treatment of chorea. Deep brain stimulation is usually reserved for patients with disabling chorea despite optimal medical therapy.

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Lower limb monochorea from a globus pallidus infarct

Cited by 4 publications

References 7 publications

Acute Stroke Presenting as Unilateral Lower Extremity Monochorea

Acute Stroke Presenting as Unilateral Lower Extremity Monochorea

Significance of N-isopropyl-[123I] p-iodoamphetamine single-photon emission computed tomography in detection of responsible hypoperfusion in hemichorea

Treatment options for chorea

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