Lower Genital Tract Disease in Children and Adolescents—A review

Heller, Debra S.

doi:10.1016/j.jpag.2004.11.015

Cited by 15 publications

(5 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As development progresses, the genito-urinary bladder, vagina and genitalia are separated from the bowel and intestinal tract by formation of the urorectal septum. In females, the bladder and urethra separate from the vagina [12,13]. Multiple congenital anomalies following the pattern of certain genitalia syndromes has been observed as in reminiscent of hydrolethalus and pseudotrisomy 13 syndrome [9].…”

Section: Discussionmentioning

confidence: 99%

Disorders of Sex Development: not Always Endocrine Disorders

2016

ARC Journal of Diabetes and Endocrinology

View full text Add to dashboard Cite

Congenital genital abnormalities are of a very complex pathology. In order to clarify their causes, it is important to revert to the genetic conditions and regulation of embryological development. The diagnostic criteria can be complex and costly. We report several patients with various isolated or multiple congenital malformations associated with ambiguous genitalia that can be elucidated by physical examination or condition specific investigations to highlight the importance of considering them in the differential diagnosis of DSD. The data was scrutinized from patients presented to Endocrine and Paediatric clinics at King Khalid University hospital (KKUH), Riyadh, Saudi Arabia, over two decades. Ninety-eight patients aged 1 day to 8 years were evaluated for DSD at KKUH between 1989-2010. Seventy percent (n=69 patients) were genetically females (46XX), while 29.6% (n=29 patients) had a male genetic sex (46XY). The majority of patients had congenital adrenal hyperplasia. However, 15.2% (n=15 patients) were diagnosed with isolated or multiple, syndromic or non-syndromic congenital anomalies. We conclude that, especially in a high consanguineous population, DSD can occur due to a wide spectrum of endocrine and non-endocrine causes. There is no substitute to careful history and physical examination in order to help the diagnosis and avoid unnecessary investigations.

show abstract

Section: Discussionmentioning

confidence: 99%

Disorders of Sex Development: not Always Endocrine Disorders

2016

ARC Journal of Diabetes and Endocrinology

View full text Add to dashboard Cite

show abstract

“…La edad promedio al diagnóstico es de 15 a 18 años. 6,7 Debe, por este motivo, recalcarse la importancia de un examen ginecológico cuidadoso en todas las niñas desde el momento del nacimiento y en casos seleccionados el examen rectal puede ser una herramienta invaluable para descartar la ausencia del útero. 5 Por la variabilidad en la longitud del canal vaginal, es importante tener en cuenta que un examen físico en apariencia normal, no descarta por completo el diagnóstico de MRKH.…”

Section: Discussionunclassified

“…En pacientes que se presentan, especialmente con dolor pélvico cíclico la laparoscopia puede ser útil para la evaluación de remanentes uterinos y la etiología del dolor pélvico. 7,12 En imágenes de RMN, la agenesia uterina y la hipoplasia pueden ser mejor caracterizadas en los cortes sagitales, mientras que la agenesia vaginal se aprecia mejor en los cortes transversales. La agenesia se demuestra como la no identifi cación del útero, mientras que la hipoplasia se observa como miometrio con señal de baja intensidad en imágenes en T2, con anatomía zonal pobremente delimitada; la cavidad endometrial y el miometrio se encuentran de tamaño disminuido.…”

Section: Discussionunclassified

Adolescente con síndrome de Mayer-von Rokitansky-Küster-Hauser: la importancia de un manejo integral multidisciplinario

Barbosa

Varela-Guzmán

2006

Rev. Colomb. Obstet. Ginecol.

View full text Add to dashboard Cite

Se presenta el caso clásico de una adolescente con diagnóstico incidental y tardío de síndrome de Mayer-von Rokitansky-Küster-Hauser y lo que consideramos aspectos fundamentales a tener en cuenta para favorecer el diagnóstico precoz y manejo de estas pacientes desde el diagnóstico inicial. Incluimos una descripción detallada de la técnica quirúrgica utilizada para reparar la anomalía, que consistió en una neovaginoplastia sigmoidea en tres tiempos sucesivos por la técnica de Peña modificada. Recalcamos la importancia del manejo multidisciplinario que involucra tanto un equipo médico calificado, como paramédicos y profesionales del área psico-social y de igual forma involucrar en todos los aspectos, la opinión de la paciente y sus padres o tutores.

show abstract

“…This has been covered in the prior review. 1 Vaginal bleeding in the newborn may be associated with withdrawal of maternal hormones.…”

Section: Menstrual Disorders In the Adolescentmentioning

confidence: 99%

“…In a previous review, 1 conditions affecting the lower genital tract of children and adolescent females were discussed. The purpose of this review is to provide an overview of conditions of the upper genital tract affecting female children and adolescents, some of which may be encountered only rarely by the more generalized practitioner.…”

Section: Introductionmentioning

confidence: 99%

Lower Genital Tract Disease in Children and Adolescents—A review

Cited by 15 publications

References 78 publications

Disorders of Sex Development: not Always Endocrine Disorders

Disorders of Sex Development: not Always Endocrine Disorders

Adolescente con síndrome de Mayer-von Rokitansky-Küster-Hauser: la importancia de un manejo integral multidisciplinario

Diseases Manifesting in the Upper Genital Tract in Children and Adolescents: A Review

Contact Info

Product

Resources

About