In a recent paper (Michalopolou A., Syskakis E. and Papastaikoudis C., 2001 J. Phys.: Cond. Matter, 13 11615) A. Michalopolou et al reported the measurements of electrical resistivity and specific heat at zero magnetic field carried out on polycrystalline non-stoichiometric La 0.95-x Sr x MnO 3 manganites. In particular, authors had attributed the low temperature behavior of resistivity (shallow minimum and slight upturn at lowest temperatures) to 3D electron-electron interaction enhanced by disorder, using results of numerical fittings of resistivity versus temperature dependencies at the interval 4.2 -40 K. It is shown in this comment that such analysis may be not valid for polycrystalline manganites where relatively strong grain boundary effects might mask weak contribution of quantum effects to low temperature resistivity. The crucial test of applicability of the theory of quantum corrections to conductivity in this case is the resistive measurements under non-zero magnetic field.