Low-temperature (100K) crystal structures of pentaaqua(5-nitrosalicylato) complexes of magnesium(II), zinc(II), cobalt(II) and nickel(II): A π–π stacked and hydrogen bonded 3D supramolecular architecture

Variation in the biomolecular interactions of nickel(ii) hydrazone complexes upon tuning the hydrazide fragment

“…The results of this study strongly support the nature of binding of DNA with complex is intercalation mode. 49 Protein binding studies Fluorescence quenching of BSA by ligands (1-3) and their metal complexes (4)(5)(6). Serum albumins are proteins that are amongst others involved in the transport of metal ions and metal complexes with drugs through the blood stream.…”

“…[4][5][6][7][8][9][10][11][12][13][14][15][16] Hydrazone ligands create an environment similar to the one present in biological systems usually by making coordination through oxygen and nitrogen atoms. Various important properties of carbonic acid hydrazides, along with their applications in medicine and analytical chemistry, have led to increased interest in their complexation characteristics with transition metal ions.…”

Nickel–quinolones interaction. Part 2 – Interaction of nickel(II) with the antibacterial drug oxolinic acid

“…Additionally, nickel complexes of biological interest have been reported with the most structurally characterized acting as antiepileptic [13], anticonvulsant [14] agents or vitamins [15] or showing antibacterial [16][17][18][19], anticancer/ antiproliferative [20][21][22][23][24][25][26], antifungal [16,27,28] and antimicrobial [29] activity. The interaction of Ni(II) complexes with DNA has been mainly dependent on the structure of the ligand exhibiting intercalative behavior [30][31][32] and/or DNA cleavage ability [33,34].…”

Nickel–quinolones interactionPart 3 — Nickel(II) complexes of the antibacterial drug flumequine

“…In this context structurally characterized nickel complexes have been able to act as antiepileptic [4], anticonvulsant [5] agents or vitamins [6] or have shown antibacterial [7][8][9], antifungal [9][10][11], antimicrobial [12] and anticancer/ antiproliferative [13][14][15][16] activity. A principal target of metals in the cancer cells is the coordination with DNA, bound selectively to it through the oxygen of phosphates and/or to heterocyclic nitrogen atoms of DNA bases [17,18].…”