Low-level laser therapy: A novel therapeutic approach to temporomandibular disorder – A randomized, double-blinded, placebo-controlled trial

Shobha, Raju; Narayanan, Vasumathi; Pai, B S Jagadish; Jaishankar, H. P.; Jijin, M J

doi:10.4103/ijdr.ijdr_345_15

Cited by 25 publications

(70 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…46,48 Collecting information of these heterogeneous clinical trials showed beneficial impacts of PBM on reducing pain at the shortterm follow-up (10 days to 4 weeks) both in the visual analog scale 36 and in the anxiety questionnaire. 46,47,[55][56][57] Among these studies, GaAlAs diode at 780 nm wavelength and 50 mW power showed the most frequent nonsignificant effects. 58,59 Functionality of TMJ was assessed in terms of maximum opening, electromyography, geometric mean diameter, colorimetric capsule method, and craniomandibular index, indicating that the total effect favored PBM in comparison with placebo.…”

Section: Indications Of Pbm For Tmdsmentioning

confidence: 99%

“…52,54,59,68,79,80 Considering the nonsignificant results, which were more common among studies that irradiated only painful points or the TMJ, 1,59,74 it seems that it is better to apply PBM on skin of both trigger points and TMJ. [46][47][48][55][56][57] Moreover, according to the results of the included studies, PBMT is more effective when administered on the muscles compared with TMJ. But, Emshoff et al 80 in a well-designed study demonstrated similar effects of PBMT and placebo, which is in accordance with Herpich et al 22 One explanation, especially for Emshoff et al's 80 findings, is their investigated patients.…”

Section: Pbm Application Sitementioning

confidence: 99%

See 1 more Smart Citation

Photobiomodulation in Temporomandibular Disorders

Tunér

Hosseinpour

Fekrazad

2019

Photobiomodulation, Photomedicine, and Laser Surgery

View full text Add to dashboard Cite

Objective: This systematic review aimed to comprehensively review all available documents regarding photobiomodulation therapy (PBMT) application in temporomandibular disorder (TMD) patients and to suggest an evidence-based protocol for therapeutic PBM administration for these patients. Background data: The existence of temporomandibular joint and/or pain and dysfunction in masticatory muscles is characterized in TMDs. PBMT is, due to its impact on biological processes, especially inflammation, considered as an adjuvant treatment modality in TMD cases. Materials and methods: All original articles related to PBMT for TMDs in EMBASE, MEDLINE (NCBI PubMed and PMC), Cochrane library, Scopus, Web of Science, and Google Scholar were reviewed until December 2018. Results: The energy density ranging from 0.75 to 112.5 J/cm 2 with 0.9-500 mW power was found to be a window protocol for light application. The best results for pain relief and mandibular movement enhancement were reported after application of GaAlAs diode laser, 800-900 nm, 100-500 mW, and <10 J/cm 2 , twice a week for 30 days on trigger points. The session of light applications varied from 1 to 20. Conclusions: Although most articles showed that PBMT is effective in reducing pain and contributed to functional enhancement in TMD patients, the heterogenic parameters that have been reported in various studies made the standardization of PBMT complicated. However, such evidence-based consensus can be beneficial for both future research and for clinical applications.

show abstract

Section: Indications Of Pbm For Tmdsmentioning

confidence: 99%

Section: Pbm Application Sitementioning

confidence: 99%

Photobiomodulation in Temporomandibular Disorders

Tunér

Hosseinpour

Fekrazad

2019

Photobiomodulation, Photomedicine, and Laser Surgery

View full text Add to dashboard Cite

show abstract

“…Risk of bias was very heterogeneous among studies. Using Cochrane Collaboration's tool, nine studies were classified as low risk of bias, 13 as unclear and 20 as high risk of bias . The higher risk of bias was reporting bias.…”

Section: Resultsmentioning

confidence: 99%

“…Out of the 42 RCTs, sample size ranged from 13 20 to 99 21 with a total of 1657 patients, mostly women, that is from 47 22 up to 100% 23-31 of the sample. Studies were conducted in Brazil, 23,26,28,30,[32][33][34][35][36][37][38][39] Canada, 24,40 China, 41 Croatia, 20 Denmark, [42][43][44] India, 45 Iran, 29,46 Italy, 21 Korea, 22 Poland, 47 Spain, 48 Sweden, [49][50][51] Thailand, 52 the Netherlands, 53 Turkey, [54][55][56] United Kingdom 57 and United States of America (USA). 25,27,31,[58][59][60][61] All studies were published in the English language.…”

Section: Study Characteristics and Results Of Individual Studiesmentioning

confidence: 99%

“…, 23,26,33,36,39,41,50,53,56 13 as unclear 20,27,30,37,38,[48][49][50][51]54,55,59,61 and 20 as high risk of bias. 21,24,25,28,29,31,32,34,40,[42][43][44][45][46][47]52,57,58,60,62 The higher risk of bias was reporting bias. Some studies provide unclear information about blinding outcome evaluators to knowledge of group allocation against detection bias, and many of them did not provide descriptions about all measurements in terms of means and standard deviation.…”

Section: -Wk Treatment Of Placebo Bidmentioning

confidence: 99%

See 1 more Smart Citation

Placebo and nocebo response magnitude on temporomandibular disorder‐related pain: A systematic review and meta‐analysis

Porporatti

Costa

Réus

et al. 2019

J of Oral Rehabilitation

View full text Add to dashboard Cite

Objectives The aim of this systematic review (SR) was to answer the following question: “In adult patients with temporomandibular disorder (TMD)‐related pain, what is the placebo or nocebo effect of different therapies?” Methods A SR was performed with randomised clinical placebo‐controlled trials on diagnosed painful TMD studies from five main databases and from three grey literature. Studies included must have sample older than 18 years, with painful TMD, which diagnosis was done by Research Diagnostic Criteria (RDC/TMD) or Diagnostic Criteria (DC/TMD). Results Out of 770 articles obtained, 42 met the inclusion criteria for qualitative and 26 for quantitative analysis. Meta‐analysis indicated mean variation on pain intensity for placebo therapy was higher on laser acupuncture with 45.5 mm point reduction, followed by avocado soya bean extract with 36 mm and amitriptyline 25 mg with 25.2 mm. Laser showed a 29% of placebo effect, as well medicine with 19% and other therapies with 26%. Possible nocebo effect of 8% pain increase was found for intra‐articular injection of Ultracain. Conclusions Based on the available data, the placebo response could play a major effect on TMD pain management and may be responsible from 10% to 75% of pain relief. Laser acupuncture, avocado soya bean and amitriptyline promoted the higher placebo effect. Possible nocebo effect was found only for Ultracain injection with 8%. Clinical Relevance Clinicians could apply such evidence to optimise pain management and judgement about treatment efficacy, and researches may find it useful when designing their investigations.

show abstract