Low-Invasive Diagnosis of Metallic Prosthesis Osseointegration by Electrical Impedance Spectroscopy

Arpaïa, Pasquale; Clemente, Fabrizio; Zanesco, A.

doi:10.1109/tim.2007.894170

Cited by 25 publications

(25 citation statements)

References 16 publications

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“…the adhesion of a greater amount of mature bone cells to the implant [Franchi et al, 2005b]. This accounts for the decrease in impedance at the implant/bone interface [Arpaia et al, 2007a] and justifies the limited increase in impedance compared to the previous time window (7-30 days).…”

Section: Discussionmentioning

confidence: 85%

“…In particular, the lower limit avoids the involvement of frequencies that show poor performance of electrodes due to electrical noise [Songer et al, 2001]; the upper limit, even if due to the capability of the proof demonstrator, assures a frequency range in which different bone prosthesis contact surfaces can be evidenced [Arpaia et al, 2007a]. The maximal electrical current admitted to flow through a living biological tissue [IEC, 2005] limits the stimulus to 320 mV.…”

Section: Measurement Setupmentioning

confidence: 99%

“…The values of the modulus, phase, real part and imaginary part of the computed impedance were recorded over the selected frequency range and stored. Only the values of the impedance modulus (IZI) over the target frequency range were found useful for the purpose of the present study, since preliminary in vitro studies had shown significant correlations between this parameter and the adherence of metal screws to the bone recipient [Arpaia et al, 2007a]. The postoperative course of the patients with implants revealed an optimal healing in 20 of them, small dehiscence around the screw that healed after platelet gel application in 5 of them and 1 case of skin overgrowth.…”

Section: Measurement Setupmentioning

confidence: 99%

“…Information about electrical characteristics of the tissues under examination is collected by delivering low-level sinusoidal currents, at a given frequency (or frequencies), by external electrodes, such as in electrical impedance spectroscopy (EIS) [Barsoukov et al, 2005]. Previous investigations have shown that EIS measurements are efficient for the evaluation of the close contact between bone and metallic implants [Arpaia et al, 2007a]. However, in order to demonstrate its clinical applicability, in vivo experimental activity needs to be carried out.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Monitoring of Fixture Osteointegration after BAHA® Implantation

Clemente¹,

Costa²,

Monini³

et al. 2010

Audiol Neurotol

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The osteointegration phase of BAHA® fixture was assessed via electrical impedance spectroscopy in BAHA® implantees. Measurements were carried out by using a prototype device and were correlated with previously published histological data obtained at certain times after surgery, i.e. 1–2 days, 1 week, 1 and 3 months. Module variations of impedance spectra were found to be in agreement with the different pathophysiological conditions of bone ingrowth. The proposed methodology has shown to be promisingly reliable to properly monitor BAHA fixture osteointegration.

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Section: Discussionmentioning

confidence: 85%

Section: Measurement Setupmentioning

confidence: 99%

Section: Measurement Setupmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Monitoring of Fixture Osteointegration after BAHA® Implantation

Clemente¹,

Costa²,

Monini³

et al. 2010

Audiol Neurotol

Self Cite

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“…Impedance measurements are widely used in several medical applications, ranging from noninvasive diagnosis [10,11] to body impedance analysis for the fat-free mass content [12] and fluid balance or in biosensors for the detection of a huge variety of different biotargets. Nevertheless, they have never been applied to allergy detection, according to the authors' knowledge.…”

mentioning

confidence: 99%

Detection of Allergen-IgE interaction in Allergic Children Through Combined Impedance and ROS Measurements

Barni

Fort

Becatti

et al. 2017

IEEE Trans. Instrum. Meas.

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Abstract-The aim of this paper is to provide an alternative and more efficient screening test for allergy with respect to traditional UNICAP and prick skin tests, which are commercially available nowadays. The proposed test is aimed at monitoring the interaction of the IgE protein with the allergen in an allergic subject. The idea relies on the fact that the interaction between the IgE and the corresponding allergen happens through binding mechanisms between the IgE and the allergen structure, changing the ionic content of the serum. This latter can be monitored by impedance measurements and confirmed by reactive oxygen species (ROS) evaluation in leukocyte subpopulations. Therefore, in this paper we propose a novel system for the detection of allergies based on impedance measurements and confirmed by ROS measurements. This type of measurement approach has never been presented in the literature for this purpose. A measurement protocol has been developed to guarantee reproducibility and repeatability of the assay. This paper describes both the instrument-specifically designed for impedance evaluationand the measurement protocols for both methodologies, defining univocally, in this way, the overall measurement technique.

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