Low-intensity exercise enhances expression of markers of alternative activation in circulating leukocytes: Roles of PPARγ and Th2 cytokines

Immune responses following McKenzie lumbar spine exercise in individuals with acute low back pain: A preliminary study

“…This may suggest that low intensity exercise, such as McKenzie exercises, may boost the M2 polarization, and thus constitute a novel exercise anti-inflammatory effect (64). Furthermore, M2a macrophage phenotypes are specifically involved in the resolution of inflammation and tissue repair process.…”

“…Further, recent studies have demonstrated that low intensity exercise, such as walking 10,000 steps/day 3/week may enhance phenotypic switching of the macrophage (M1 to M2) (62)(63)(64). This may suggest that low intensity exercise, such as McKenzie exercises, may boost the M2 polarization, and thus constitute a novel exercise anti-inflammatory effect (64).…”

GALNT2 mRNA levels are associated with serum triglycerides in humans

“…As an additional limitation of our study, we acknowledge that, although PWBC are an easily obtainable cell model widely used for studying gene expression changes in insulin resistance and related abnormalities [5,[7][8][9], they are not involved in lipid metabolism, thus leaving open the question whether or not our data can be translated into pathophysiological mechanisms controlling serum triglycerides levels. Thus, present data have to be considered as a preliminary, hypothesis generating, finding that needs to be deeper addressed by additional studies in cells responsible of lipid metabolism, including hepatocytes and adipocytes.…”

Affective Response And Pain Measurement Correlations In A 500 Mile Pilgrimage: El Camino De Santiago

“…A study performed by Yakeu et al (2010) demonstrated that low intensity exercise could up-regulate the expression of the M2 marker and activate the nuclear receptor PPARy nuclear receptor, both of which have been linked to an improved inflammatory response. The researchers found that the PPARy activation by means of low intensity exercise was very similar to the activation of the receptor by pharmacological means, and so exercise could be used as a reliable means of reducing inflammation in the body (Yakeu et al, 2010). These studies demonstrate the value of exercise for diabetic patients and also prove the necessity for long term exercise adherence in order to see the full spectrum of positive benefits linked to physical activity.…”