Low Grade Myofibroblastic Sarcoma in Postauricular Area : A Case Report

Lee, Dong-Kun; Park, Heon-Soo; Rha, Seo-Hee; Ahn, Joong-Ki

doi:10.35420/jcohns.2010.21.2.253

Cited by 2 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The differential diagnosis of LGMS includes a variety of benign or malignant lesions, including nodular fasciitis, IMT, fibrosarcoma and leiomyosarcoma 12 . Fibrosarcomas are composed of malignant spindle cells showing fibroblastic differentiation, which are distinguished from myofibroblasts by the absence of immunohistochemical evidence of fibronectin and SMA 13 . Leiomyosarcomas show more eosinophilic and longitudinally fibrillary cytoplasm and cigar-shaped vesicular nuclei with paranuclear vacuolation.…”

Section: Discussionmentioning

confidence: 99%

Low-Grade Myofibroblastic Sarcoma on Back with Repeated Localized Recurrence and Regional Metastasis

Park,

Choi,

Chae

et al. 2023

Ann Dermatol

View full text Add to dashboard Cite

Low-grade myofibroblastic sarcoma (LGMS) is a rare spindle cell tumor with indolent course. Due to rarity and low-grade histologic features of LGMS, accurate diagnosis is challenging. We report a 63-year-old female patient with a three-month history of a 3.1 cm×2.5 cm sized, firm, skin-colored, painless, protruding left back mass. Initial excisional biopsy was performed and the mass was diagnosed as nodular fasciitis. After 18 months after excision, the mass recurred with pain and grew larger. Considering the clinical manifestations, diagnostic impression was changed as dermatofibrosarcoma protuberans not nodular fasciitis. Second wide excision was performed and the histopathology revealed proliferative atypical spindle cells with moderate nuclear atypia and a distinctive whorling pattern, which is suggestive of low-grade sarcoma. Additional computed tomography and positron emission tomography revealed no metastasis and suspicious residual viable malignant tissue. To remove suspicious residual tumor, third wide excision were performed and the diagnosis confirmed as LGMS. A microscopically clear resection was achieved with deep and lateral safety margin 0.6 cm each. Despite of postoperative radiotherapy with 35 times, recurrence of the tumor and lung metastasis was found after 7 months later. LGMS rarely metastasizes and occurs most commonly in the head and neck region. Thus, we report a rare case of LGMS on back which repeated localized recurrence and regional lung metastasis occurred despite wide excision and adjuvant radiotherapy.

show abstract

Section: Discussionmentioning

confidence: 99%

Low-Grade Myofibroblastic Sarcoma on Back with Repeated Localized Recurrence and Regional Metastasis

Park,

Choi,

Chae

et al. 2023

Ann Dermatol

View full text Add to dashboard Cite

show abstract

“…This disease occurs mainly in the head and neck region, and rarely invades multiple organs. 2,3 We report here a rare case of LGMS that occurred in multiple organs, including the diaphragmatic pleura, and head and neck region. Because surgery and radiotherapy are not suitable for patients with multiple metastases, novel systemic treatments are required to improve the cure rate.…”

Section: Introductionmentioning

confidence: 96%

Low-grade myofibroblastic sarcoma with abdominal pain, a stuffy nose, hearing loss, and multiple cavity effusion: a case report and literature review

Guo

Shaoying³

et al. 2020

J Int Med Res

View full text Add to dashboard Cite

Low-grade myofibroblastic sarcoma (LGMS) is a rare, low-grade, malignant tumor and is mainly composed of myofibroblasts with varying degrees of differentiation. LGMS results in considerable diagnostic difficulty. We report a case of LGMS that occurred in multiple organs, including the diaphragmatic pleura, and head and neck region. A 34-year-old man was hospitalized in 2014 after coughing and shortness of breath for 10 days, and abdominal distension, abdominal pain, and bilateral lower extremity edema for 4 days. Before this admission, he had an abdominal tumor diagnosed in 1994 and 2003, a nasopharynx tumor in 2010, and a temporal lobe tumor in 2013. All tumors were resected surgically and the diagnosis was atypical fibrous histiocytoma and atypical fibrous xanthoma. Before surgeries for these tumors, no positron emission tomography-computed tomography (PET-CT) or whole-body scans were performed, and after surgery, there was no follow-up. After thoracoscopy and PET-CT after the most recent admission, the patient was diagnosed with LGMS with metastasis to the bone, nodes, and thoracic and abdominal cavities. The patient was discharged with albumin infusion treatment. Although LGMS is rare, it is potentially serious. Therefore, clinicians should be aware of such disease and make an early diagnosis and perform close follow-up.

show abstract

Low Grade Myofibroblastic Sarcoma in Postauricular Area : A Case Report

Cited by 2 publications

References 8 publications

Low-Grade Myofibroblastic Sarcoma on Back with Repeated Localized Recurrence and Regional Metastasis

Low-Grade Myofibroblastic Sarcoma on Back with Repeated Localized Recurrence and Regional Metastasis

Low-grade myofibroblastic sarcoma with abdominal pain, a stuffy nose, hearing loss, and multiple cavity effusion: a case report and literature review

Contact Info

Product

Resources

About