Low-grade fibromyxoid sarcoma of the medial vastus: a case report

Abstract

Low-grade fibromyxoid sarcoma (LGFMS) was first described by Evans in 1987, and since then, just over 150 cases have been reported, showing the rarity of this tumor. We report the clinical case of a 56-year-old man with a swelling on the distal third of the left thigh. The mass had grown in the course of 1 year and was surgically excised, obtaining complete resolution. Immuno-histological examination demonstrated the lesion to be a LGFMS, defined as a benign tumor but with a high incidence of local and distant recurrence (5-10%). At 2-year follow-up the patient was disease-free, confirming the efficacy of the surgical excision. In literature, the frequency of incomplete excision of LGFMS due to inappropriate diagnosis is stressed. It is this element that contributes most to the high rate of recurrence. We recommend that the eventuality of observing this rare tumor be borne in mind, and that care be taken to perform a complete, ample excision.

A rare case report of pancreatic low-grade fibromyxoid sarcoma (LGFMS)

“…Low-grade fibromyxoid sarcoma (LGFMS) is a rare tumor generally arising from soft tissues of the inguinal region, thoracic wall, and shoulder [ 5 ]. LGFMS has also been described in the mesentery of the small bowel, mesocolon, colon, and liver [ 6 – 9 ].…”

“…Similar to other sarcomas, it often affects adults in the fourth decade. Even when occurring in muscle tissue, it is rare, with around 150 cases reported since it was first described in 1987 [ 5 ]. Microscopically, it appears as a bland spindle cell neoplasm.…”