Low‐fluence 585 nm Q‐switched Nd:YAG laser: A novel laser treatment for post‐acne erythema

Panchaprateep, Ratchathorn

doi:10.1002/lsm.22321

Cited by 21 publications

(59 citation statements)

References 33 publications

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“…Both ablative and non‐ablative lasers have been used in the treatment of acne, particular acne scars . In addition to the post‐acne scaring benefits, non‐ablative laser treatments may also be effective in reducing erythema and post acne inflammation . Non‐ablative treatments using radio frequency (RF) have been reported to be effective for the treatment of mild acne.…”

Section: Discussionmentioning

confidence: 99%

Low‐level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne

Fassih

Binner

et al. 2017

Lasers Surg Med

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Section: Discussionmentioning

confidence: 99%

Low‐level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne

Fassih

Binner

et al. 2017

Lasers Surg Med

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“…Postacne erythema (PAE) remains to be a therapeutic challenge as there are no reliable treatment guidelines available. Although some lesions may spontaneously improve over time, some may continue to last for 2‐6 months 12 or in some cases, complete clearance may not be achieved at all. Several laser modalities aiming to target dilated blood vessels have been utilized in the past to help improve the appearance of PAE.…”

Section: Discussionmentioning

confidence: 99%

“…9,10 The 585 and 595-nm lasers target oxyhemoglobin in blood vessels, while the 1550-nm wavelength targets water causing heat production and as a result, photothermal destruction of dermal vasculature. [11][12][13][14] Intense pulsed light (IPL) provides a noncoherent polychromatic source of intense light ranging from 400 to 1200-nm. The vascular mode of IPL operates at 560-nm, which allows for more selective destruction of superficial vessels by allowing peak absorption of oxyhemoglobin at 577-nm.…”

Section: Introductionmentioning

confidence: 99%

The efficacy and safety of a 577‐nm high‐power optically pumped semiconductor laser in the treatment of postacne erythema

Wanitphakdeedecha

Cembrano

Ungaksornpairote

et al. 2020

J of Cosmetic Dermatology

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Background Postacne erythema (PAE) is a common sequela of inflammatory acne vulgaris, treatment of which has been challenging due to limited options available and the variability of results for each modality. Recently, a 577‐nm high‐power optically pumped semiconductor laser (HOPSL) initially developed for vascular lesions has shown promising results for the treatment of PAE. Aims To evaluate the efficacy and safety of 577‐nm HOPSL in the treatment of postacne erythema. Methods This was a split‐face, randomized controlled trial pilot study. Twenty‐one patients with PAE on both sides of their face were enrolled. Each subject's face sides were randomly assigned to either receive 577‐nm HOPSL treatment (QuadroStar PRO™, Asclepion Laser Technologies) using the scanner handpiece, 1mm spot size, 80% coverage, 12‐15 J/cm2, 30 ms, 2 passes for 3 sessions at 1‐month intervals, or no treatment at all. Outcome measures such as overall improvement, the Erythema Index (EI), and Melanin Index (MI) from 3 different areas on both treatment and control sides were assessed at baseline, and 1‐month follow‐up after each treatment session. Side effects including pain, erythema, swelling, and crusting were also recorded. Results Upon completion of the treatment period, the mean EI was significantly decreased in both treated and nontreated sides of the face (P < .001 and P = .001, respectively). The laser‐treated sides already demonstrated significant reduction in the mean EI compared with nontreated sides at 1 month after the 2nd treatment (P = .007). The mean MI of both sides, however, did not show any statistically significant differences from baseline, and likewise when comparing between sides. Patients reported more improvement on laser‐treated sides compared with nontreated sides. Reported side effects were limited to mild discomfort during treatment and transient facial erythema lasting approximately 30 minutes. Conclusion Patients who received treatment with the 577‐nm HOPSL had better outcomes with minimal side effects at 1 month after 2 treatments as compared to those who did not receive any treatment. Therefore, the 577‐nm HOPSL may be considered as an effective adjuvant treatment for PAE and early erythematous atrophic scars.

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“…This might be from the higher energy usage or difference of Fitzpatrick skin type. The lower fluent usage in our study may not have penetrated deeply enough to destroy these inflammatory microvessels . We designed our study to use this fluency because the participants’ Fitzpatrick skin types in our study were 4–5, which differed from the Yoon study.…”

Section: Discussionmentioning

confidence: 99%

“…Nowadays, it is very challenging to discover the best therapy for acne vulgaris especially in adolescents because the disease is may not have penetrated deeply enough to destroy these inflammatory microvessels. 15 We designed our study to use this fluency because the participants' Fitzpatrick skin types in our study were 4-5, which differed from the Yoon study.…”

Section: Discussionmentioning

confidence: 99%

Randomized, controlled trial split‐faced study of 595‐nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood

et al. 2017

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The high prevalence of acne vulgaris in teenagers has increased comorbidities. Lasers offer alternative options for acne treatment because they have rapid action, low systemic adverse effects, and do not require everyday treatment. To study the efficacy and patients' satisfaction of 595-nm pulse dye laser (PDL) treatment of acne vulgaris and acne erythema in adolescents and early adulthood, we designed a blocked-randomized, split-faced 595-nm PDL (fluence 8 J/cm pulse duration 10 ms, spot size 7 mm, 2 session every 2 weeks) study in patients with mild to moderate acne by comparing the laser-treated and non-treated side. The acne lesion counts, acne erythema grading, and acne severity grading were evaluated at baseline and 2, 4, and 8 weeks. Thirty patients were recruited. The results showed no statistically significant difference except the papule count at week 4 which was -1.828 on the treated side and 0.103 on the non-treated side of the face, P-value 0.0018. There was no statistically significant difference of acne severity grading and acne erythema grading between both sides of the face. The mean scores of patients' satisfaction on the laser-treated side were 75, 81, and 81%, respectively. The PDL treatment in this study reveals no significant improvement in acne therapy; however, the patients were satisfied with this laser treatment.

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Low‐fluence 585 nm Q‐switched Nd:YAG laser: A novel laser treatment for post‐acne erythema

Abstract: Low-fluence 585 nm Q-switched Nd:YAG laser treatment is safe and effective for the treatment of post-acne erythema with minimal discomfort and quantifiable improvement in the appearance of early acne scarring and inflammatory acne.

Cited by 21 publications

References 33 publications

Low‐level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne

Low‐level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne

The efficacy and safety of a 577‐nm high‐power optically pumped semiconductor laser in the treatment of postacne erythema

Randomized, controlled trial split‐faced study of 595‐nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood

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