Low-fat Diet After Cholecystectomy: Should It Be Systematically Recommended?

Blasco, Yolanda; Muñante, Mónica Pérez; Gómez-Fernández, Laura; Jovell-Fernández, Esther; Bernad, L.M. Oms

doi:10.1016/j.cireng.2019.12.006

Cited by 6 publications

(9 citation statements)

References 22 publications

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“…In order to determine whether the associations between cholecystectomy and sarcopenia were influenced by insulin resistance, we additionally adjusted for the HOMA‐IR in the models. We found that the associations between cholecystectomy and sarcopenia were attenuated but remained significant, suggesting that, in addition to insulin resistance, other factors (e.g., decreased level of 25‐hydroxyvitamin D and changing diet after a cholecystectomy) may also play a role (5,6,30,31,32).…”

Section: Discussionmentioning

confidence: 93%

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Sarcopenia and sarcopenic obesity after cholecystectomy: A population‐based study

Gan

Wang

et al. 2021

Obesity

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Objective: The present study aimed to investigate the associations of cholecystectomy with low muscle mass, low muscle strength, sarcopenia, and sarcopenic obesity. Methods:This population-based study included data from 4,909 participants aged 18 to 80 years. History of cholecystectomy was diagnosed using abdominal ultrasonography. Muscle mass was evaluated using a dual-energy x-ray absorptiometry scan, and muscle strength was evaluated using an electronic hand dynamometer.Sarcopenia was defined as the presence of both low muscle mass and low muscle strength. Sarcopenic obesity was defined as the presence of both sarcopenia and obesity. Multivariable logistic regression models were performed to investigate the associations of cholecystectomy with low muscle mass, low muscle strength, sarcopenia, and sarcopenic obesity.Results: Participants with history of cholecystectomy were more likely than those without to have low muscle mass, low muscle strength, and sarcopenia. Furthermore, compared with cholecystectomy that occurred within 7 years (7 years is the median interval between cholecystectomy and the physical examination), participants with cholecystectomy that occurred more than 7 years ago had higher odds of sarcopenia. Finally, whether obesity was defined by BMI or body fat percentage, cholecystectomy was positively associated with sarcopenic obesity. Conclusions:Cholecystectomy is associated with low muscle mass, low muscle strength, sarcopenia, and sarcopenic obesity.

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Section: Discussionmentioning

confidence: 93%

“…Cholecystectomy has long been regarded as innocuous. Recent studies have found that cholecystectomy was associated with insulin resistance, nonalcoholic fatty liver diseases (3,4), and change in dietary pattern (5,6), which are associated with sarcopenia (7,8). However, whether cholecystectomy is associated with sarcopenia remains unclear.…”

Section: Introductionmentioning

confidence: 99%

Sarcopenia and sarcopenic obesity after cholecystectomy: A population‐based study

Gan

Wang

et al. 2021

Obesity

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“…In a study conducted by Blasco et al, dietary changes were made to target the fat content in 83 patients who had cholecystectomy. The study found that there was no discernible difference in the impact of low-fat content on the rate of improvement of post-operative symptoms [ 16 ]. As the GB is an organ of storage rather than bile production, there is currently no good reason to restrict a patient's diet during the post-operative phase of a cholecystectomy.…”

Section: Reviewmentioning

confidence: 99%

Dietary Considerations in Cholecystectomy: Investigating the Impact of Various Dietary Factors on Symptoms and Outcomes

Dahmiwal,

Zade,

Tote

et al. 2024

Cureus

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Cholecystectomy is commonly performed to address gallstone diseases, including the development of gallstones, which can lead to symptoms such as nausea, vomiting, and abdominal pain. Bile acids (BAs) produced by the liver are primarily stored and concentrated in the gallbladder (GB). After cholecystectomy, the body's ability to digest lipids is reduced due to the absence of the GB. Post-cholecystectomy syndrome (PCS) can occur when abdominal symptoms manifest after surgery. The purpose of this review is to look at the various effects of different dietary factors on patients undergoing cholecystectomy, how they affect their overall health after surgery, and how they contribute to symptoms of PCS. Some individuals may experience mild discomfort or alterations in bowel patterns, especially after consuming high-fat meals. The findings from the conducted studies suggest that, although dietary changes are a common recommendation, these measures are not sufficiently supported by evidence when it comes to alleviating symptoms and improving outcomes post-cholecystectomy. The studies found that subjects who consumed particular foods, such as processed meat and fried fatty foods, had exacerbated symptoms after cholecystectomy. Further studies are still required to understand the precise food factors that might affect post-surgical symptoms, as well as outcomes, and to develop tailored measures to enhance patient care and long-term prognosis after undergoing cholecystectomy.

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“…[ 4 ] The 2020 Canadian Chronic Diarrhea Guidelines highlight cholecystectomy as a risk factor for chronic diarrhea. [ 7 ] In addition, Ribas et al [ 8 ] found that >50% of patients had abnormal bowel habits after cholecystectomy, of which 23% had unrelieved symptoms after 6 months.…”

Section: Introductionmentioning

confidence: 99%

“…[ 9 ] However, a recent study showed that a low-lipid diet did not improve the symptoms in patients with PCD. [ 8 ] In addition, owing to the lack of sufficient clinical data and negative publicity of media reports, there is no conclusive evidence of the true clinical effect of dietary interventions. [ 10 ] In addition, nearly a quarter of patients with PCD take different types of bile-binding drugs, of which colestyramine is the most frequently used.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of Chinese herbal medicine in treating postcholecystectomy diarrhea: A systematic review and meta-analysis

Sun,

Zhang,

Wang

et al. 2024

Medicine

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Background: Postcholecystectomy diarrhea (PCD) is among the most distressing and well-known clinical complications of cholecystectomy. Despite various available treatment options, clinical outcomes are greatly limited by unclear pathophysiological mechanisms. Chinese herbal medicine (CHM) is widely used as a complementary and alternative therapy for the treatment of functional diarrhea. Thus, we conducted a meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of CHM for the treatment of PCD. Methods: Electronic database searches were conducted using the Cochrane Library, PubMed, Web of Science, Embase, Wanfang Data, China National Knowledge Infrastructure, and the Chinese Scientific Journal Database. All RCTs on CHMs for managing patients with PCD were included. The meta-analysis was performed using RevMan 5.4 software. Results: The present meta-analysis included 14 RCTs published between 2009 and 2021 in China. The primary findings indicated that CHM had a higher total efficacy and cure rate as a monotherapy for PCD (P < .00001). Two trials reported the scores of the main symptoms with statistically significant differences in stool nature (P < .00001), defecation frequency (P = .002), and abdominal pain and bloating (P < .00001). In addition, CHM reduced CD3 + and CD4 + levels more effectively in terms of T lymphocyte subset determination (P < .00001). The main symptoms of PCD in traditional Chinese medicine (TCM) are splenic deficiency and liver stagnation. All treatments were used to strengthen the spleen and (or) soothing the liver. Conclusion: CHM had a favorable effect on PCD. No adverse events were observed. Larger, high-quality RCTs are warranted to draw definitive conclusions and standardize treatment protocols.

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Low-fat Diet After Cholecystectomy: Should It Be Systematically Recommended?

Cited by 6 publications

References 22 publications

Sarcopenia and sarcopenic obesity after cholecystectomy: A population‐based study

Sarcopenia and sarcopenic obesity after cholecystectomy: A population‐based study

Dietary Considerations in Cholecystectomy: Investigating the Impact of Various Dietary Factors on Symptoms and Outcomes

Efficacy and safety of Chinese herbal medicine in treating postcholecystectomy diarrhea: A systematic review and meta-analysis

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