Low-cost and rapid prototyping of microfluidic paper-based analytical devices by inkjet printing of permanent marker ink

Xu, Chunxiu; Cai, Longfei; Zhong, Ming; Zheng, Shuyue

doi:10.1039/c4ra13195a

Cited by 58 publications

(33 citation statements)

References 26 publications

(24 reference statements)

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“…Devices were developed from conceptualization to use in as little as 1 h without the need for photomasks or any specialized equipment except for a commercially available FDM printer. These print times are somewhat longer and more expensive than other commonly-used hydrophobic µPAD materials such as wax 28 – 32 and ink resins 33 , 34 , but the numerous substrates capable of being 3D-printed allows barrier materials to be chosen based on application. For instance, materials can be printed that exhibit low bioanalyte absorption unlike polydimethylsiloxane 35 or those that are compatible with organic solvents unlike many waxes or chemical modification methods 36 .…”

Section: Resultsmentioning

confidence: 99%

Hybrid 3D printed-paper microfluidics

Zargaryan

Farhoudi

Haworth

et al. 2020

Sci Rep

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3D printed and paper-based microfluidics are promising formats for applications that require portable miniaturized fluid handling such as point-of-care testing. These two formats deployed in isolation, however, have inherent limitations that hamper their capabilities and versatility. Here, we present the convergence of 3D printed and paper formats into hybrid devices that overcome many of these limitations, while capitalizing on their respective strengths. Hybrid channels were fabricated with no specialized equipment except a commercial 3D printer. Finger-operated reservoirs and valves capable of fully-reversible dispensation and actuation were designed for intuitive operation without equipment or training. Components were then integrated into a versatile multicomponent device capable of dynamic fluid pathing. These results are an early demonstration of how 3D printed and paper microfluidics can be hybridized into versatile lab-on-chip devices.

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Section: Resultsmentioning

confidence: 99%

Hybrid 3D printed-paper microfluidics

Zargaryan

Farhoudi

Haworth

et al. 2020

Sci Rep

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“…Paper-based microfluidic chip is formed by infiltrating hydrophobic materials into hydrophilic paper fibers through various methods, controlling the fluid flow in hydrophilic paper fibers through the "wall" of hydrophobic materials, thus forming a paper-based microfluidic chip. Common inkjet printers [38], screen printing [39], 3D printers [40], wax printers [41] and even crayons [42] can be used to process low-cost, paper-based microfluidic chips. In the choice of paper, the common ones are Whatman series filter paper [43] or chromatographic paper [44].…”

Section: Paper Materialsmentioning

confidence: 99%

Application of Microfluidic Chip Technology in Food Safety Sensing

Gao

Yan

et al. 2020

Sensors

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Food safety analysis is an important procedure to control food contamination and supervision. It is urgently needed to construct effective methods for on-site, fast, accurate and popular food safety sensing. Among them, microfluidic chip technology exhibits distinguish advantages in detection, including less sample consumption, fast detection, simple operation, multi-functional integration, small size, multiplex detection and portability. In this review, we introduce the classification, material, processing and application of the microfluidic chip in food safety sensing, in order to provide a good guide for food safety monitoring.

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“…Inkjet printing is not a cutting-edge technology in microfluidics or biosensors; this method has already been demonstrated numerous times, especially in paper-based microfluidic devices. Inkjet printing can be used for printing substrates, patterning channels, and depositing assay reagents [ 75 , 76 , 77 , 78 , 79 ]. Inkjet printing involves two main modes of operation: continuous mode and drop-on-demand mode (Liu et al discuss these methods in depth [ 80 ]).…”

Section: State-of-the-art Microfluidic Devices For Iron Deficiencymentioning

confidence: 99%

Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia

Yap

Soair

Talik

et al. 2018

Sensors

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Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection.

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Low-cost and rapid prototyping of microfluidic paper-based analytical devices by inkjet printing of permanent marker ink

Abstract: μPADS were fabricated by inkjet printing of permanent marker ink on filter paper, followed by evaporation of solvent.

Cited by 58 publications

References 26 publications

Hybrid 3D printed-paper microfluidics

Hybrid 3D printed-paper microfluidics

Application of Microfluidic Chip Technology in Food Safety Sensing

Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia

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