Low-Cardiac-Output Syndrome After Cardiac Surgery

Lomivorotov, Vladimir V.; Efremov, Sergey; Kirov, Mikhail Y.; Fominskiy, Evgeny; Karaskov, Alexander

doi:10.1053/j.jvca.2016.05.029

Cited by 228 publications

(209 citation statements)

References 193 publications

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“…This difference was attributed to the probable difference in age. Neonatal myocardium is physiologically immature [18][19][20][21] and every procedure affects the incidence of LCOS differently [22]. The age range of children included in this study was larger (1-6457 days), and we included different types of cardiac surgery.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for low cardiac output syndrome in children with congenital heart disease undergoing cardiac surgery: a retrospective cohort study

Chen

Song

et al. 2020

BMC Pediatr

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Background: Low cardiac output syndrome (LCOS) is an important complication of cardiac surgery. It is associated with increased morbidity and mortality. The incidence of LCOS after surgery is high in patients with congenital heart disease (CHD). Therefore, determining the risk factors of LCOS has clinical significance for the management of CHD. This study aimed to analyze the risk factors of LCOS. Methods: We conducted a retrospective analysis of children with CHD who underwent cardiac surgery at Shanghai Children's Medical Center between January 1, 2014, and December 31, 2017. Demographic characteristics and baseline data were extracted from the health data resource center of the hospital, which integrates clinical routine data including medical records, diagnoses, orders, surgeries, laboratory tests, imaging, nursing, and other subsystems. Logistic regressions were performed to analyze the risk factors of LCOS. Results: Overall, 8660 infants with CHD were included, and 864 (9.98%) had LCOS after surgery. The multivariate regression analysis identified that age (OR 0.992, 95% CI: 0.988-0.997, p = 0.001), tricuspid regurgitation (1.192, 1.072-1.326, p = 0.001), Risk Adjustment in Congenital Heart Surgery-1 risk grade (1.166, 1.011-1.345, p = 0.035), aortic shunt (left-to-right: 1.37, 1.005-1.867, p = 0.046; bi-directional: 1.716, 1.138-2.587, p = 0.01), atrial shunt (left-toright: 1.407, 1.097-1.805, p = 0.007; right-to-left: 3.168, 1.944-5.163, p < 0.001; bi-directional: 1.87, 1.389-2.519, p < 0.001), ventricular level shunt (left-to-right: 0.676, 0.486-0.94, p = 0.02; bi-directional: 2.09, 1.611-2.712, p < 0.001), residual shunt (3.489, 1.502-8.105, p = 0.004), left ventricular outflow tract obstruction (3.934, 1.673-9.254, p = 0.002), right ventricular outflow tract obstruction (3.638, 1.225-10.798, p = 0.02), circulating temperature (mild hypothermia: 1.526, 95% CI: 1.205-1.934, p < 0.001; middle and low temperature: 1.738, 1.236-2.443, p = 0.001), duration of cardiopulmonary bypass (1.009, 1.006-1.012, p < 0.001), myocardial preservation using histidine-tryptophanketoglutarate (1.677, 1.298-2.167, p < 0.001), and mitral insufficiency (1.714, 1.239-2.37, p < 0.001) were independent risk predictors of LCOS. Conclusions: The incidence of postoperative LCOS in CHD children remains high. Circulation temperature, myocardial preservation using histidine-tryptophan-ketoglutarate, and usage of residual shunt after surgery were independent risk predictors for LCOS.

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Section: Discussionmentioning

confidence: 99%

Risk factors for low cardiac output syndrome in children with congenital heart disease undergoing cardiac surgery: a retrospective cohort study

Chen

Song

et al. 2020

BMC Pediatr

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“…З а даними досліджень, летальність у пацієнтів похилого та старечого віку після проведення аортокоронарного шунтування становить від 3 до 11 %, тоді як ускладнення виникають у 30-40 % випадків [12]. Одне з найтяжчих порушень, яке може спостерігатися в ранній післяопераційний період та яке безпосередньо загрожує життю пацієнта, -це гостра серцева недостатність [13].…”

Section: оригінальні дослідженняunclassified

Risk factors for postoperative mortality with intra-aortic balloon counterpulsation in the early period after coronary artery bypass surgery in elderly and geriatric patients

Druzhyna¹,

Лоскутов²,

Maruniak³

et al. 2019

CSIC

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“…Over the decades, mortality in cardiac surgery has decreased, despite an increase in surgical complexity 76 . However, PHF continues to be among the most important causes of mortality associated with cardiac surgery and aortic valve interventions 6,77 .…”

Section: Myocardial Dysfunction In Aortic Valve Surgerymentioning

confidence: 99%

“…Pre-and postoperative characteristics. 70 [65][66][67][68][69][70][71][72][73][74][75][76] 75 [68][69][70][71][72][73][74][75][76][77][78][79] 0.08 60 <0.001 82 [76][77][78][79][80][81][82][83][84][85] Values are given as n (%) and median (25 th to 75 th percentile).…”

Section: Study IIImentioning

confidence: 99%

Implications of myocardial dysfunction before and after aortic valve intervention

Hultkvist

2019

Linköping University Medical Dissertations

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Low-Cardiac-Output Syndrome After Cardiac Surgery

Cited by 228 publications

References 193 publications

Risk factors for low cardiac output syndrome in children with congenital heart disease undergoing cardiac surgery: a retrospective cohort study

Risk factors for low cardiac output syndrome in children with congenital heart disease undergoing cardiac surgery: a retrospective cohort study

Risk factors for postoperative mortality with intra-aortic balloon counterpulsation in the early period after coronary artery bypass surgery in elderly and geriatric patients

Implications of myocardial dysfunction before and after aortic valve intervention

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