Low birth weight profiles at H. Boejasin Hospital, South Borneo, Indonesia in 2010-2012

Astria, Yuni; Suwita, Christopher S.; Suwita, Benedicta Mutiara; Widjaya, Felix F.; Rohsiswatmo, Rinawati

doi:10.14238/pi56.3.2016.155-61

Cited by 6 publications

(5 citation statements)

References 17 publications

(19 reference statements)

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“…The prevalence of LBW in Indonesia has increased from 2002 to 2013, namely 9.30% to 10.2%. This is linear with the situation of infant mortality due to LBW in Indonesia is still high, namely 29% 4 .…”

Section: Introductionmentioning

confidence: 85%

Socioeconomic Disparities of Low Birth Weight in Rural Indonesia

Laksono

Wulandari

Matahari

2020

Preprint

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Background: Poverty is estimated to increase a mother's chances of giving birth to a low birth weight baby (LBW). Objective: This study aimed to analyze the socioeconomic disparities of LBW in rural Indonesia.Methods: Mother aged 15-49 years old who had given birth in the last 5 years in rural Indonesia was used as the unit of analysis. With stratification and multistage random sampling found 19,283 mothers were sampled. The variables analyzed included LBW, socioeconomic, age, marital, education, employment, and antenatal care (ANC). The binary logistic regression test was used at the final stage to determine the existence of disparities.Results: The results show that the mother with the poorer wealth status was 0.686 times more likely than the poorest mother to give birth to an LBW baby. Mothers with middle wealth status were 0.688 times more likely than the poorest mothers to give birth to LBW babies. Mothers with richer wealth status were 0.621 times more likely than the poorest mothers to give birth to LBW babies. Finally, the richest mothers were 0.452 times more likely than the poorest mothers to give birth to LBW babies. The results of this analysis inform that the better the socioeconomic of mothers, the lower the likelihood of giving birth to LBW babies. Apart from socioeconomics, the analysis also found two other predictors of LBW in rural Indonesia, namely education level and ANC visits.Conclusion: It was concluded that there were socioeconomic disparities of LBW in rural Indonesia.

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Section: Introductionmentioning

confidence: 85%

Socioeconomic Disparities of Low Birth Weight in Rural Indonesia

Laksono

Wulandari

Matahari

2020

Preprint

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“…This might be because we excluded neonates with gestational age less than 34 week gestational age, which usually have lower birth weight. 17,18 The mechanism responsible for the increase of RDW in neonatal sepsis is not yet clearly described. Inflammatory cytokines can modulate erythropoiesis with two pathways (1) suppression of erythroid cell maturation in bone marrow or (2) inhibition of Epo gene transcription in the kidney or liver.…”

Section: Discussionmentioning

confidence: 99%

Red Cell Distribution Width Value Supports the Diagnosis of Neonatal Sepsis in 34-42 Week Gestational Age Neonates

Stevanny

Akbari²,

Mariana

2021

J. Nepal Paedtr. Soc.

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Introduction: Neonatal sepsis is an emergency because delayed treatment can be fatal, whereas the diagnosis is challenging because of the unspecific clinical manifestation. Bacterial culture is the gold standard for the diagnosis, but it takes several days to get the results, which often come out as negative. This study aims to determine the diagnostic value of RDW to support the diagnosis of neonatal sepsis in 34 – 42 week gestational age neonates. Methods: This cross-sectional diagnostic study used secondary data obtained from Medical Record Installation and Clinical Pathology Laboratory of Dr. Mohammad Hoesin General Central Hospital in Palembang, Indonesia. One hundred and thirty-four medical records were statistically analysed using Med Calc Version 19 to determine the cut-off point and diagnostic value of RDW in the diagnosis of neonatal sepsis. Results: One hundred and thirty-four subjects consisting 32 septic neonates (23.9%) and 102 non-septic neonates (76.1%) were reviewed. Most of them were males (80/134) and preterm (73/134) with normal birth weight (99/134). At the cut-off point of > 16.2%, RDW value was significantly able to predict neonatal sepsis (p = 0.000, p < α) with prediction power (AUC) of 0.780 (fair). The diagnostic values were sensitivity 84.37%, specificity 57.84%, positive predictive value 38.57%, negative predictive value 92.19%, positive likelihood ratio 2.00 and negative likelihood ratio 0.27. Conclusions: Red cell distribution width value might potentially be used as a diagnostic marker to support the diagnosis of neonatal sepsis in 34 – 42 week gestational age neonates. However, further study is needed to support this statement.

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“…Secara fisiologis, kadar bilirubin meningkat setalah lahir kemudian menetap dan akan menurun setelah usia bayi 7 hari. 5 Hiperbilirubinemia merupakan masalah yang sering terjadi pada bayi baru lahir terlebih bayi dengan berat lahir rendah dengan penyebab multifaktorial. Keadaan ini sering dianggap sebagai hal yang fisiologik tanpa mengetahui bahwa ikterus pada bayi dapat menyebabkan kerusakan organ tubuh lainnya.…”

Section: Pendahuluanunclassified

Mekanisme Terjadinya Hiperbilirubinemia pada Bayi Berat Lahir Rendah

Gerungan

Wilar

Mantik

2022

eCL

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Hyperbilirubinemia is frequently found in newborns, especially in low birth weight (LBW) infants (less than 2,500 g). Hyperbilirubinemia is an increase in bilirubin higher than 5 mg/dL which clinically manifests as icterus. This study aimed to evaluate the relationship between LBW and the incidence of hyperbilirubinemia as well as the underlying mechanism. This was a literature study. Article searching used databases of Pubmed and Google Schoolar and the keywords were Hyperbilirubinemia AND Low birth weight NAD Neonatal Jaundice. The results showed a relationship between LBW and the incidence of hyperbilirubinemia. There were increases of hemoglobin, heme catabolism, and destruction of bilirubin due to liver immaturity, impaired liver function and perfusion and bilirubin conjugation ability, less of albumin as the transportation protein and uridine diphosphate glucuronyltransferase (UDP-GT) to convert indirect bilirubin to direct bilirubin in the liver. In conclusion, there is a relationship between low birth weight and hyperbilirubinemia that occurs due to liver immaturity, impaired liver function and perfusion, and less of albumin and UDP-GT enzyme.Keywords: hyperbilirubinemia; low birth weight; neonatal jaundice Abstrak: Hiperbilirubinemia merupakan masalah yang sering terjadi pada bayi baru lahir terlebih bayi dengan berat lahir rendah (<2.500 gram). Hiperbilirubinemia merupakan peningkatan kadar bilirubin serum >5mg/dL yang bermanifestasi klinis berupa ikterus. Penelitian ini bertujuan untuk mengetahui hubungan antara BBLR dengan kejadian hiperbilirubinemia dan mekanisme terjadinya. Jenis penelitian ialah suatu literature review. Pencarian artikel menggunakan Pubmed dan Google Schoolar dengan kata kunci Hyperbilirubinemia AND Low birth weight AND Neonatal Jaundice. Hasil penelitian mendapatkan adanya hubungan antara BBLR dengan kejadian hiperbilirubinemia. Terdapat peningkatan jumlah hemoglobin, katabolisme heme dan penghan-curan bilirubin yang terjadi antara lain karena imaturitas hati yang belum optimal mengkonju-gasikan bilirubin, terganggunya fungsi dan perfusi hati serta kemampuan mengkonjugasi bilirubin, rendahnya kadar protein albumin sebagai transportasi dan enzim uridin difosfat glukoronid transferase (UDP-GT) untuk mengonversi bilirubin indirek menjadi bilirubin direk di dalam hati. Simpulan penelitian ini ialah terdapat hubungan antara BBLR dengan hiperbilirubinemia yang dapat terjadi karena imaturitas hati, terganggunya fungsi dan perfusi hati, serta kurangnya protein albumin dan enzim UDP-GT.Kata kunci: hiperbilirubinemia; low birth weight; neonatal jaundice

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Low birth weight profiles at H. Boejasin Hospital, South Borneo, Indonesia in 2010-2012

Abstract: Background The prevalence of low birth weight (LBW) is still

Cited by 6 publications

References 17 publications

Socioeconomic Disparities of Low Birth Weight in Rural Indonesia

Socioeconomic Disparities of Low Birth Weight in Rural Indonesia

Red Cell Distribution Width Value Supports the Diagnosis of Neonatal Sepsis in 34-42 Week Gestational Age Neonates

Mekanisme Terjadinya Hiperbilirubinemia pada Bayi Berat Lahir Rendah

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