Low 25-hydroxyvitamin D levels in postmenopausal female patients with benign paroxysmal positional vertigo

Wei, Han; Fan, Zhenyi; Zhou, Min; Guo, Xu; Lu, Xiaoxiong; Li, Li; Gu, Chengyao; Chen, Caijing; Wu, Yunqin

doi:10.1080/00016489.2017.1416168

Cited by 34 publications

(31 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…59,60 The vitamin D level is particularly low in postmenopausal women with BPPV. 61 A low vitamin D level is associated with osteoporosis, and medication to treat osteoporosis can provide protection against BPPV and reduce the incidence of recurrence. 62,63 Talaat et al 64 reported that the rate of recurrence of BPPV in patients with an elevated serum vitamin D level following replacement therapy was quite low during the follow-up period (4%) when compared with that in patients with a low serum vitamin D level (43%).…”

Section: Osteoporosis and Vitamin D Insufficiencymentioning

confidence: 99%

Review of the pathology underlying benign paroxysmal positional vertigo

Yetışer

2019

J Int Med Res

View full text Add to dashboard Cite

The pathophysiological mechanism underlying benign paroxysmal positional vertigo (BPPV) is related to free-floating debris/otoliths in the semicircular canal (canalolithiasis) or debris/otoliths attached to the cupula (cupulolithiasis). These debris/otoliths are considered to originally accumulate after detachment from the neuroepithelium of the utricular macula secondary to a type of degeneration. An idiopathic form, which is assumed to occur spontaneously, is diagnosed when the causative pathology is obscure. However, an association between various other systemic or inner ear conditions and BPPV has been reported, indicating the existence of secondary BPPV. This study was performed to present the first review of the pathology underlying BPPV following a complete PubMed/Medline search. In total, 1932 articles published from 1975 to 2018 were reviewed. The articles were classified according to 17 potentially causative factors (aging; migraine; Meniere's disease; infection; trauma; idiopathic sudden sensorineural hearing loss; sleeping habits; osteoporosis and vitamin D insufficiency; hyperglycemia and diabetes mellitus; chronic head and neck pain; vestibule or semicircular canal pathology; pigmentation disorders; estrogen deficiency; neurological disorders; autoimmune, inflammatory, or rheumatologic disorders; familial or genetic predisposition; and allergy). A discussion of the underlying cause of BPPV for each factor is presented.

show abstract

Section: Osteoporosis and Vitamin D Insufficiencymentioning

confidence: 99%

Review of the pathology underlying benign paroxysmal positional vertigo

Yetışer

2019

J Int Med Res

View full text Add to dashboard Cite

show abstract

“…Lack of muscle mass and muscle strength occurs as important organic changes by aging and is remarkably associated with an elevated risk of falls and subsequent osteoporotic fractures, besides this severely influences the potential of movement (Orsatti et al, 2011[26]; Muir and Montero-Odasso, 2011[25]). Vitamin D deficiency is common among older populations worldwide, as more than 60 % of postmenopausal women are vitamin D deficient, regardless of other nutrient deficiencies (Rizzoli et al, 2006[30]; Holick, 2007[20]; Han et al, 2018[17]). In observational studies, optimal serum 25(OH)D levels have been significantly associated with improved musculoskeletal function and muscle strength (Bischoff-Ferrari et al, 2004[6]; Visser et al, 2003[36]).…”

Section: Introductionmentioning

confidence: 99%

The effects of vitamin D supplementation on muscle function among postmenopausal women: a systematic review and meta-analysis of randomized controlled trials

Tabrizi

Hallajzadeh

Mirhosseini

et al. 2019

EXCLI Journal; 18:Doc591; ISSN 1611-2156

View full text Add to dashboard Cite

“…Han et al also found that on post-menopausal women the mean serum vitamin D3 levels were significantly lower in patients with primary BPPV than controls (19.1 ± 5.2 versus 22.5 ± 5.8, P value < 0.001). 17 Sen et al reported that mean serum vitamin D3 levels in patients with BPPV and healthy controls were 20.3 ± 12.2 and 18 ± 10.1 ng/mL, respectively. The prevalence of vitamin D3 deficiency among the BPPV patients and controls was 76% and 42%, respectively.…”

Section: Discussionmentioning

confidence: 99%

Investigating the Association Between Serum Vitamin D Deficiency and Idiopathic Benign Paroxysmal Positional Vertigo

Dhameliya

Chandra

Vishwakarma

et al. 2020

Int Clin Neurosci J

View full text Add to dashboard Cite

Background: It is suggested that there is a positive association between vitamin D deficiency and benign paroxysmal positional vertigo (BPPV). We suggest, as a hypothesis, there is a positive association between vitamin D deficiency and BPPV. The current study aimed to investigate the association between vitamin D levels and BPPV. Methods: The present observational case-control study was planned and conducted on 100 participants (50 cases and 50 controls) in the Department of Neurology, Choithram Hospital & Research Center (CHRC), Indore, MP, India, from January 2018 to December 2018. All consecutive patients with diagnosis of idiopathic BPPV who were above the age of 18 years with a negative neurological status were included. Analyses were performed using SPSS software version 10. Results: BPPV was more common among those aged 50 to 70 years (64%). Out of 100 participants, 72 (72%) had vitamin D deficiency, in which 40 (80%) were cases and 32 (64%) were controls. 32 (64%) patients had posterior canal involved, out of them 20 (40%) were females and 12 (24%) were males, and in both groups posterior canal was more involved. Canal involvement according to gender was not statistically significant (P value=0.45). Mean vitamin D level for cases and controls was 34.9 and 46.5 nmol/L, respectively, and this difference was statically very significant with a p-value of 0.01 (P value < 0.05). Conclusion: According to the findings, there is a statistically significant association between vitamin D3 deficiency and Idiopathic BPPV. It can be noted that vitamin D3 deficiency may be a risk factor for the BPPV.

show abstract

Low 25-hydroxyvitamin D levels in postmenopausal female patients with benign paroxysmal positional vertigo

Abstract: Our study suggests that low 25 (OH) D may be a risk factor for BPPV in postmenopausal women.

Cited by 34 publications

References 18 publications

Review of the pathology underlying benign paroxysmal positional vertigo

Review of the pathology underlying benign paroxysmal positional vertigo

The effects of vitamin D supplementation on muscle function among postmenopausal women: a systematic review and meta-analysis of randomized controlled trials

Investigating the Association Between Serum Vitamin D Deficiency and Idiopathic Benign Paroxysmal Positional Vertigo

Contact Info

Product

Resources

About