Loquat (Eriobotrya japonica (Thunb) Lindl.): Evaluation of nutritional value, polyphenol composition, antidiabetic effect, and toxicity of leaf aqueous extract

Khouya, Tarik; Ramchoun, Mhamed; Elbouny, Hamza; Hmidani, Abdelbassat; Bouhlali, Eimad dine Tariq; Alem, Chakib

doi:10.1016/j.jep.2022.115473

Cited by 21 publications

(7 citation statements)

References 31 publications

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“…Ash is a reflection of the amount of mineral elements in the samples and, therefore, serves as the main source of mineral elements needed for human and animal health. Loquat leaves have a high amount of minerals, especially potassium, calcium, magnesium, iron, and sodium [ 20 ]. We speculated that the high content found in this study may depend on soil characteristics.…”

Section: Discussionmentioning

confidence: 99%

Chemical Characterization and In Vitro Gas Production Kinetics of Alternative Feed Resources for Small Ruminants in the Maltese Islands

et al. 2023

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The ever-increasing human population, the problem associated with climate change and recent crises—COVID-19 disease and trade conflicts—all impacted on the availability and cost of animal feed raw materials. This is clearly visible in realities which heavily rely on importation such as islands and small states, where producers involved in the agricultural sector were strongly affected by the sharp increase in prices. To deal with these global issues, alternative resources are perceived to replace conventional ingredients. This work aimed at assessing the nutritive value of different resources (sheep feed, mature carob, Maltese bread, wild asparagus, prickly lettuce, and loquat) for small ruminants present in the Maltese Islands, analyzing their chemical composition, gas production kinetics and antioxidant properties. In general, the variation in chemical composition resulted in different rumen fermentation kinetics (p < 0.007). The ratio between GP-24 h and GP-48 h was higher in Maltese bread than other substrates; loquat, prickly lettuce and wild asparagus showed lower fermentation kinetics in accordance with their high NDF and ADF contents. The antioxidant activity may be partially related to the polyphenolic content that was higher in wild asparagus, prickly lettuce and loquat. All feed characteristic confirmed their potential to be included as ingredients in ruminant diets and as a source of fiber.

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Section: Discussionmentioning

confidence: 99%

Chemical Characterization and In Vitro Gas Production Kinetics of Alternative Feed Resources for Small Ruminants in the Maltese Islands

et al. 2023

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“…(2022). 26 The concentration of total polyphenols, expressed as milligrams of gallic acid equivalent per gram of extract (mg GAE/g extract), was determined from a gallic acid calibration curve equation.…”

Section: Methodsmentioning

confidence: 99%

Phytochemical analysis, antioxidant, and antihyperlipidemic activities of Teucrium takoumitense

El-Guourrami,

Elbouny,

Ait Benlabchir

et al. 2023

Journal of Taibah University Medical Sciences

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“…The total flavonoid content of extracts was determined by the aluminum trichloride colorimetric method as described by Khouya et al, (2022). To generate the calibration curve, rutin was used a standard flavonoid compound (Khouya et al, 2022).…”

Section: Determination Of Total Flavonoid Content (Tfc)mentioning

confidence: 99%

In vitro investigations of biological activities of Thymus willdenowii and Thymus atlanticus polyphenol-rich extracts

Elbouny

Ouahzizi

Sellam

et al. 2023

International Journal of Secondary Metabolite

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Thyme species produce a wide variety of phenolic compounds including tannins, phenolic acids, and flavonoids. Thymus atlanticus (T. atlanticus) and Thymus willdenowii (T. willdenowii) are important thyme species in the southeast of Morocco, with numerous biological properties. The polyphenolic extracts of these two thyme species were obtained using ethanol through Soxhlet apparatus. Antioxidant (DPPH, FRAP, and TAC methods), antihemolytic (2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) induced hemolysis test), hypolipidemic (3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity inhibition test), and anti-inflammatory (protein denaturation inhibition) effects of extracts were carried out using in vitro methods. The results showed that the polyphenolic extracts of these two species revealed important amounts of phenolic compounds. The contents of flavonoids were significant in the two species, while the contents of tannins and anthocyanin were very low. T. atlanticus showed an important antioxidant activity and a considerable antihemolytic effect in AAPH-induced hemolysis test (IC50 = 0.29 mg/mL), while T. willdenowii showed an important anti-inflammatory activity in heat-induced protein denaturation test (IC50 = 1.61 mg/mL). Moreover, both extracts at a dose of 20 µg/mL showed an important in vitro hypolipidemic activity by inhibiting HMG-CoA reductase activity (T. willdenowii: 51.16 %; T. atlanticus: 62.83 %). In conclusion, T. willdenowii and T. atlanticus extracts have considerable antioxidant, antihemolytic, hypolipidemic, and anti-inflammatory effects. The richness of these species in polyphenols gives them a large specter of biological properties, making them a valuable source of natural bioactive compounds that could prevent or treat various diseases.

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Loquat (Eriobotrya japonica (Thunb) Lindl.): Evaluation of nutritional value, polyphenol composition, antidiabetic effect, and toxicity of leaf aqueous extract

Cited by 21 publications

References 31 publications

Chemical Characterization and In Vitro Gas Production Kinetics of Alternative Feed Resources for Small Ruminants in the Maltese Islands

Chemical Characterization and In Vitro Gas Production Kinetics of Alternative Feed Resources for Small Ruminants in the Maltese Islands

Phytochemical analysis, antioxidant, and antihyperlipidemic activities of Teucrium takoumitense

In vitro investigations of biological activities of Thymus willdenowii and Thymus atlanticus polyphenol-rich extracts

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