Loose anagen hair as a cause of hereditary hair loss in children

Is the Loose Anagen Hair Syndrome a Keratin Disorder?

“…The clinical presentation of children in our series is similar to that of other cases reported in the literature. 4,5,[8][9][10][11][12][13][14][15][16][17][18][19][20] The children have slowgrowing hair that seldom requires cutting. 4,5,[8][9][10][11][12][13][14][15][16][17][18][19]21,22 Parents may also be worried by the patients' diffuse hair loss or localized patches of alopecia.…”

“…4,5,[8][9][10][11][12][13][14][15][16][17][18][19][20] The children have slowgrowing hair that seldom requires cutting. 4,5,[8][9][10][11][12][13][14][15][16][17][18][19]21,22 Parents may also be worried by the patients' diffuse hair loss or localized patches of alopecia. 4,5,[8][9][10][11][12][13][14][15][16]19,22,23 They may have easily pluckable hair, although this sign is not always obvious.…”

“…4,5,[8][9][10][11][12][13][14][15][16][17][18][19]21,22 Parents may also be worried by the patients' diffuse hair loss or localized patches of alopecia. 4,5,[8][9][10][11][12][13][14][15][16]19,22,23 They may have easily pluckable hair, although this sign is not always obvious. 9,10,[12][13][14][15]19,21,23 However, as in our series, the pull test result is usually positive, with more than 50% of dystrophic anagen hairs per pull in pediatric cases of LAHS.…”

Descrição de nova distrofia macular associada à síndrome dos cabelos anágenos frouxos

“…É conhecido na literatura internacional com o nome de "loose anagen hair syndrome (LAHS) (6) ". A herança é autossômica dominante e os achados essenciais são: os cabelos serem facilmente retirados do couro cabeludo quando puxados, estes se encontrarem na fase anágena e há a ausência da camada externa e interna da raiz (7) . Os achados característicos na microscopia eletrônica de varredura (MEV) são a presença de formações canaliculares que ocorrem ao longo do folículo piloso (4,8) .…”

Distrofia retiniana com onda rápida escotópica (DRORE) associada à síndrome dos cabelos anágenos frouxos (SCAF). Parte I: Achados oftalmológicos

“…Esses cabelos são facilmente retirados do couro cabeludo e de forma indolor (2) . A herança é autossômica dominante, e os achados essenciais são: 1) cabelos facilmente retirados do couro cabeludo quando puxados; 2) encontramse na fase anágena e 3) há ausência das bainhas radiculares externa e interna (3) . Os achados característicos na microscopia eletrônica de varredura (MEV) são a presença de formações canaliculares que ocorrem ao longo do folículo piloso e enrugamento da cutícula próxima à raiz (2) .…”