Looking at the Missing Brain: Hydranencephaly Case Series and Literature Review

Cecchetto, Giovanni; Milanese, Laura; Giordano, R; Viero, Alessia; Suma, V.; Manara, Renzo

doi:10.1016/j.pediatrneurol.2012.10.009

Cited by 67 publications

(71 citation statements)

References 37 publications

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“…41 In our cohort, patient II.1 from family H showed severe brain destruction with undetectable medial cerebral arteries, resembling hydranencephaly, at 33 weeks' gestation. The child was stillborn at 34 weeks of gestational age.…”

Section: Sporadic Extensive Bilateral Porencephaly Resembling Hydranementioning

confidence: 59%

The expanding phenotype of COL4A1 and COL4A2 mutations: clinical data on 13 newly identified families and a review of the literature

Meuwissen

Halley

Smit

et al. 2015

Genetics in Medicine

220

234

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Section: Sporadic Extensive Bilateral Porencephaly Resembling Hydranementioning

confidence: 59%

The expanding phenotype of COL4A1 and COL4A2 mutations: clinical data on 13 newly identified families and a review of the literature

Meuwissen

Halley

Smit

et al. 2015

Genetics in Medicine

220

234

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“…The management of hydranencephaly is still controversial. Some authors are abstinent; others choose surgery by defending fair arguments [29][30][31][32][33][34][35]. In our department, we prefer surgery.…”

Section: Discussionmentioning

confidence: 99%

A Technique for Treatment of Overdrainage in Ventriculoperitoneal Shunt

Kpelao

Békéti

Moumouni

et al. 2017

IrJNS

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Background and Importance:Overdrainage is a complication of ventriculoperitoneal shunt but adjustable valves and anti-siphon devices can prevent it. These very expensive valves are most often inaccessible, so that the majority of the valves available in Togo are fixed differential pressure valves. Although overdrainage is a widely-known issue, we aimed to introduce a new risk factor and the way we manage this complication.Case Presentation: This case series study included all patients who had overdrainage or a high potential risk of overdrainage (hydranencephaly). Our technique consisted of partial ligation of the peritoneal catheter at the level of the thorax by non-resorbable wire while controlling the drainage rate at the slots. The goal was to transform this fixed differential pressure valve into a pressure-controlled and flow-regulated one. Patients were followed for 1, 3 and 6 months, postoperatively. Conclusion:Hydranencephaly predisposes patients to overdrainage. The partial ligature of the catheter is an effective technique for treating or preventing overdrainage.

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“…However, there are two problems with this argument. First, levels of remaining cortical tissues vary widely from case to case (Cecchetto et al (2013)), and in the few children that survived with hydranencephaly and who are not in a vegetative state, there is no precise assessment of the remaining cortical tissues. Without a specific assessment of the levels of unimpaired cortical tissue for each of these cases it is difficult to draw any conclusions over the possibility of having experiences without a cerebral cortex.…”

Section: The Multiple Realization Argumentmentioning

confidence: 99%

Fish and microchips: on fish pain and multiple realization

Michel¹

2018

Philos Stud

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Opponents to consciousness in fish argue that fish do not feel pain because they do not have a neocortex, which is a necessary condition for feeling pain. A common counter-argument appeals to the multiple realizability of pain: while a neocortex might be necessary for feeling pain in humans, pain might be realized differently in fish. This paper argues, first, that it is impossible to find a criterion allowing us to demarcate between plausible and implausible cases of multiple realization of pain without running into a circular argument. Second, opponents to consciousness in fish cannot be provided with reasons to believe in the multiple realizability of pain. I conclude that the debate on the existence of pain in fish is impossible to settle by relying on the multiple realization argument.

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Looking at the Missing Brain: Hydranencephaly Case Series and Literature Review

Cited by 67 publications

References 37 publications

The expanding phenotype of COL4A1 and COL4A2 mutations: clinical data on 13 newly identified families and a review of the literature

The expanding phenotype of COL4A1 and COL4A2 mutations: clinical data on 13 newly identified families and a review of the literature

A Technique for Treatment of Overdrainage in Ventriculoperitoneal Shunt

Fish and microchips: on fish pain and multiple realization

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