Longitudinal Follow-up of Tinnitus Complaints

Andersson, Gerhard; Vretblad, Pernilla; Larsen, Hans Christian; Lyttkens, Leif

doi:10.1001/archotol.127.2.175

Cited by 96 publications

(68 citation statements)

References 18 publications

(22 reference statements)

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“…In previous clinical trials with the MML as the efficacy outcome variable, such a relationship has indeed been observed [Jastreboff et al, 1994;Davis et al, 2007]. Additionally, a longitudinal study by Andersson et al [2001] showed that tinnitus maskability is an important prognostic factor for future tinnitus annoyance. This is illustrated by the fact that many patients are actively seeking sources of masking in their daily life to diminish tinnitus perception.…”

Section: Efficacymentioning

confidence: 70%

Safety of Intratympanic Injection of AM-101 in Patients with Acute Inner Ear Tinnitus

Muehlmeier

Biesinger²,

Maier

2011

Audiol Neurotol

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Effective pharmacological treatments for tinnitus have proven elusive. Emerging evidence suggests that dysregulation of cochlear N-methyl-D-aspartate (NMDA) receptors may underlie aberrant excitation of the auditory nerve, which in turn is perceived as tinnitus. The blocking of these receptors thus represents a promising therapeutic approach. In a recent phase I/II clinical trial, the safety and local tolerance of intratympanic injections of the NMDA receptor antagonist AM-101 was evaluated for the first time in humans. The results from the double-blind, randomized, placebo-controlled study show that intratympanically injected AM-101 was well tolerated by study participants, and provided the first indications of therapeutic efficacy.

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Section: Efficacymentioning

confidence: 70%

Safety of Intratympanic Injection of AM-101 in Patients with Acute Inner Ear Tinnitus

Muehlmeier

Biesinger²,

Maier

2011

Audiol Neurotol

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“…Exposure to noise is responsible for the most common cause of tinnitus 37,38 , reported by about 25% of the individuals exposed to it 6,38 . In this series, tinnitus prevalence was of approximately 48%, much higher than the one reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

Interação entre grau de perda auditiva e o incômodo com zumbidos em trabalhadores com história de exposição ao ruído

Días¹,

Cordeiro²

2008

Rev. Bras. Otorrinolaringol.

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Heari ng loss and tinnitus impact the lives of workers in every instance of their lives. Aim: this paper aims to investigate the existence of a dose-response relationship between hearing loss and tinnitus by determining whether higher levels of hearing loss can be associated with increased tinnitus-related discomfort. Materials and method: this cross-sectional case study assessed 284 workers exposed to occupational noise through pure tone audiometry. Test results were categorized as defined by Merluzzi. Individuals complaining of tinnitus answered the adapted and validated Brazilian Portuguese version of the Tinnitus Handicap Inventory. A generalized linear model was adjusted for binomial data to test the interaction between these factors. Results: over 60% of the ears analyzed had hearing loss, while more than 46% of them had tinnitus. Tinnitus prevalence and risk rates increased as pure tone audiometry results got worse. The association between both, considering all hearing loss degrees, was statistically significant. Conclusion: the results point to a statistical association between hearing loss and tinnitus; the greater the hearing loss, the greater the discomfort introduced by tinnitus.

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“…They found that tinnitus distress might continue despite having tinnitus for 4.9 years, but that tolerance to tinnitus decreased. Much of the literature regarding treatment response to tinnitus indicates a lack of long-term outcomes except for those people that received cognitive behavioural therapy for tinnitus [59]. Therefore, despite treatment, …”

Section: Coping Stylesmentioning

confidence: 99%

Situationally influenced tinnitus coping strategies: a mixed methods approach

Beukes

Manchaiah

Andersson

et al. 2017

Disability and Rehabilitation

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tinnitus coping strategies: A mixed methods approach AbstractPurpose The primary aim of this study was to identify coping strategies used to manage problematic tinnitus situations. A secondary aim was to determine whether different approaches were related to the level of tinnitus distress, anxiety, depression and insomnia experienced. Results There were 240 participants (137 males, 103 females), with an average age of 48.16 years (SD: 22.70). Qualitative content analysis identified eight problematic tinnitus situations. Participants had either habituated to their tinnitus (7.9%), used active (63.3%) or passive (28.8%) coping styles to manage these situations. Those who had habituated to tinnitus or used active coping strategies had lower levels of tinnitus distress, anxiety, and depression. Materials and Methods ConclusionsThe main problematic tinnitus situations for this cohort were identified. Both active and passive coping styles were applied to approach these situations. The coping strategies used most frequently and utilised in the widest range of problematic situations were using sound enrichment and diverting attention..

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Longitudinal Follow-up of Tinnitus Complaints

Abstract: Severe tinnitus shows some signs of improvement over time, especially when psychological treatment has been given. Tinnitus maskability is an important prognostic factor of future tinnitus annoyance.

Cited by 96 publications

References 18 publications

Safety of Intratympanic Injection of AM-101 in Patients with Acute Inner Ear Tinnitus

Safety of Intratympanic Injection of AM-101 in Patients with Acute Inner Ear Tinnitus

Interação entre grau de perda auditiva e o incômodo com zumbidos em trabalhadores com história de exposição ao ruído

Situationally influenced tinnitus coping strategies: a mixed methods approach

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