1988
DOI: 10.3109/00016348809004215
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Longitudinal Changes in Blood Viscosity Are Correlated With Fetal Outcome

Abstract: The importance of longitudinal changes in maternal Whole Blood Viscosity (WBV) for fetal well-being was investigated. Consecutive WBV data were available, obtained from 44 pregnancies before 36 0/7 weeks. An increase in WBV was found to be associated with an unfavorable fetal outcome. This result might be considered as clinical evidence supporting the hypothesis that maternal WBV contains information on the efficacy of placental perfusion.

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Cited by 4 publications
(2 citation statements)
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“…This theory is supported by evidence of the role of elevated blood viscosity for impaired efficiency of maternal blood flow (Ha et al, 2001). Increased blood viscosity is associated with decreased oxygen diffusion (Zondervan et al, 1988) and may interfere with the supply of oxygen and nutrients to the fetus. In addition, some toxicants from air pollutants could cross the placenta with direct effects on fetal development (Dejmek et al, 1999).…”
Section: Biological Mechanismsupporting
confidence: 49%
“…This theory is supported by evidence of the role of elevated blood viscosity for impaired efficiency of maternal blood flow (Ha et al, 2001). Increased blood viscosity is associated with decreased oxygen diffusion (Zondervan et al, 1988) and may interfere with the supply of oxygen and nutrients to the fetus. In addition, some toxicants from air pollutants could cross the placenta with direct effects on fetal development (Dejmek et al, 1999).…”
Section: Biological Mechanismsupporting
confidence: 49%
“…59,60 Indeed, high iron intake can have undesirable effects through diverse mechanisms including oxidative stress due to reactive oxygen species and, probably, by inducing hemoconcentration leading to elevated blood viscosity, poor placental perfusion, and risk of preeclampsia. [61][62][63][64] Risk of low birth weight, premature delivery, and of small-for-gestationalage deliveries have been documented among pregnant women with hemoconcentration, especially during the second and early third trimesters. 33,36,58,[65][66][67][68][69]…”
Section: How Do Maternal Iron Status and Health Influence Pregnancy Omentioning
confidence: 99%