Air Pollution and Adverse Pregnancy Outcome

Leem, Jong-Han; Ha, Eun–Hee

doi:10.5772/20214

Cited by 2 publications

(3 citation statements)

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“…(3) the scores were summed up for each mother with the total score ranging from 7 to 23; (4) the total scores were classified as followslow (7)(8)(9)(10)(11)(12), medium (13)(14)(15)(16)(17)(18) and high (19)(20)(21)(22)(23) HAP exposure.…”

Section: Practical Implicationsmentioning

confidence: 99%

“…The exact biological mechanisms underlying the air pollution—maternal disorders of pregnancy relationship also remain unexplored 18 . Some studies have pointed to oxidative stress, placental inflammation, impairments in DNA transcription, and imbalance in angiogenic factors as key underlying mechanisms of these pregnancy‐related conditions 19–21 …”

Section: Introductionmentioning

confidence: 99%

“…18 Some studies have pointed to oxidative stress, placental inflammation, impairments in DNA transcription, and imbalance in angiogenic factors as key underlying mechanisms of these pregnancy-related conditions. [19][20][21] Diet, especially vitamin D rich foods, has been identified to play a key role in reducing women's risk of developing maternal disorders of pregnancy. Adequate vitamin D intake during pregnancy is essential for improving maternal health.…”

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confidence: 99%

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Vitamin D intake modifies the association of household air pollution exposure with maternal disorders of pregnancy

et al. 2021

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Air pollution, which comprises ambient air pollution and household air pollution (HAP), is one of the largest environmental risk factors and contributes to about 7 million deaths worldwide. 1 In 2016, HAP resulted in an estimated 3.8 million premature deaths, equivalent to 6.7% of global mortality and is greater than deaths due to malaria, tuberculosis, and HIV/AIDS combined. 2 HAP is predominantly generated from the use of solid fuels, such as wood, coal and charcoal for cooking, heating and lightning. In some settings, burning of garbage is another important source of HAP. 3 Currently, about 41% of households globally rely on solid fuels as their primary cooking fuel

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Section: Practical Implicationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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confidence: 99%

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Vitamin D intake modifies the association of household air pollution exposure with maternal disorders of pregnancy

et al. 2021

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A meta-analysis of exposure to particulate matter and adverse birth outcomes

Lamichhane

Leem

Lee

et al. 2015

Environ Health Toxicol

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ObjectivesThe objective of this study was to conduct a systematic review to provide summarized evidence on the association between maternal exposure to particulate air pollution and birth weight (BW) and preterm birth (PTB) after taking into consideration the potential confounding effect of maternal smoking.MethodsWe systematically searched all published cohort and case-control studies examining BW and PTB association with particulate matter (PM, less than or equal to 2.5μm and 10.0 μm in diameter, PM2.5 and PM10, respectively) from PubMed and Web of Science, from January 1980 to April 2015. We extracted coefficients for continuous BW and odds ratio (OR) for PTB from each individual study, and meta-analysis was used to combine the coefficient and OR of individual studies. The methodological quality of individual study was assessed using a standard protocol proposed by Downs and Black. Forty-four studies met the inclusion criteria.ResultsIn random effects meta-analyses, BW as a continuous outcome was negativelyassociated with 10 μg/m3 increase in PM10 (-10.31 g; 95% confidence interval [CI], -13.57 to -3.13 g; I-squared=0%, p=0.947) and PM2.5 (-22.17 g; 95% CI, -37.93 to -6.41 g; I-squared=92.3%, p <0.001) exposure during entire pregnancy, adjusted for maternal smoking. A significantly increased risk of PTB per 10 μg/m3 increase in PM10 (OR, 1.23; 95% CI, 1.04 to 1.41; I-squared=0%, p =0.977) and PM2.5 (OR, 1.14; 95% CI, 1.06 to 1.22; I-squared=92.5%, p <0.001) exposure during entire pregnancy was observed. Effect size of change in BW per 10 μg/m3 increase in PM tended to report stronger associations after adjustment for maternal smoking.ConclusionsWhile this systematic review supports an adverse impact of maternal exposure to particulate air pollution on birth outcomes, variation in effects by exposure period and sources of heterogeneity between studies should be further explored.

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Air Pollution and Adverse Pregnancy Outcome

Cited by 2 publications

References 118 publications

Vitamin D intake modifies the association of household air pollution exposure with maternal disorders of pregnancy

Vitamin D intake modifies the association of household air pollution exposure with maternal disorders of pregnancy

A meta-analysis of exposure to particulate matter and adverse birth outcomes

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