Longitudinal association between physical activity and blood pressure, risk of hypertension among Chinese adults: China Health and Nutrition Survey 1991–2015

Zou, Qinpei; Wang, Huijun; Su, Chang; Du, Wenwen; Yu, Ouyang; Jia, Xiaofang; Wang, Zhihong; Ding, Gangqiang; Zhang, Bing

doi:10.1038/s41430-020-0653-0

Cited by 25 publications

(18 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…NHANES used a complex, stratified sampling design, which can select representative samples of non-institutionalized civilians. Participants underwent a detailed in-home interview and a physical examination and blood specimen collection at specially equipped mobile examination centers [ 28 ]. The study was conducted in accordance with the Declaration of Helsinki [ 29 ].…”

Section: Methodsmentioning

confidence: 99%

Serum 25-hydroxyvitamin D might be negatively associated with hyperuricemia in U.S. adults: an analysis of the National Health and Nutrition Examination Survey 2007–2014

Han

Zhang

et al. 2021

J Endocrinol Invest

View full text Add to dashboard Cite

Purpose The results of previous studies on the relationship between serum 25-hydroxyvitamin D [25(OH)D] and hyperuricemia are controversial. We hypothesized that serum 25(OH)D concentrations of U.S. adults would negatively correlate with the risk of hyperuricemia. Method Data came from the National Health and Nutrition Examination Survey 2007–2014 were used, after excluding those who met at least one of the exclusion criteria, a total of 9096 male individuals and 9500 female individuals aged 18 years or older were included. Binary logistic regression analysis and restricted cubic spline with fully adjusted confounding factors were applied to evaluate the association between serum 25(OH)D and hyperuricemia. We further performed stratified analysis and sensitivity analysis to minimize the influence of gender, metabolic syndrome, obesity and renal dysfunction on the above association. Results We found a negative correlation between serum 25(OH)D and hyperuricemia. In the binary logistic regression analysis, compared with the highest serum 25(OH)D quartile [Q4: 25(OH)D > 77.10 nmol/L] group, the odds ratios (95% confidence intervals) in the lowest quartile [Q1: 25(OH)D ≤ 43.20 nmol/L] was 1.46 (1.22–1.75) in the fully adjusted model. Restricted cubic spline analysis showed L-shaped and non-linear relationships between 25(OH)D and hyperuricemia. In sensitivity analysis, after restricting to participants without significant renal dysfunction and obesity, the above association remained significant. After restricting to participants who were diagnosed as metabolic syndrome, above association remained significant in the fully adjusted model. In stratified analysis by gender, the association remained significant among males and females. Conclusions Serum 25(OH)D might be inversely associated with hyperuricemia in general U.S. adults. From our study, for people with unexplained hyperuricemia, screening for serum Vitamin D concentration might be necessary.

show abstract

Section: Methodsmentioning

confidence: 99%

Serum 25-hydroxyvitamin D might be negatively associated with hyperuricemia in U.S. adults: an analysis of the National Health and Nutrition Examination Survey 2007–2014

Han

Zhang

et al. 2021

J Endocrinol Invest

View full text Add to dashboard Cite

show abstract

“…Serum uric acid is measured by Hitachi 7600 automated analyzer using an enzymatic colorimetric method. Triplicate measurements of BP were taken after 10 min at sitting and with at least 1 min between recordings with the use of mercury sphygmomanometer and means of the three BP measurements were used in the final analysis ( 20 ). Participants who met at least one of the following criteria: SBP ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg, using antihypertensive drugs during the previous 2 weeks, or ever diagnosed with hypertension by a physician ( 21 ).…”

Section: Methodsmentioning

confidence: 99%

Serum Uric Acid Might Be Positively Associated With Hypertension in Chinese Adults: An Analysis of the China Health and Nutrition Survey

Han

et al. 2022

Front. Med.

View full text Add to dashboard Cite

Background: Previous studies have clarified the relationship between serum uric acid (SUA) and hypertension; most of previous studies suggest that elevated uric acid levels are associated with an increased risk of hypertension, while in China, there are relatively few studies to explore above association. The objective of this longitudinal study is to investigate the correlation of SUA and hypertension in Chinese adults with a nationwide large-scale sample.Methods: Data from the China Health and Nutrition Survey 2009, 2011, and 2016 were used; a total of 8,469 participants (3,973 men and 4,496 women) were involved. This study was conducted separately by gender. Clinical characteristics of the participants among different uric acid groups are compared. The binary logistic regression analysis was conducted to examine the association between SUA and hypertension. Restricted cubic spline analysis with three knots of the SUA concentration were used to characterize the dose-response relationship. Additionally, we compared the incidence of hypertension in the different baseline uric acid groups during follow-up in 2011 and 2015.Results: After the covariates were fully adjusted, we found that elevated uric acid levels were correlated with increased risk of hypertension in both males (p < 0.01) and females (p < 0.01). With 2-year or 6-year of follow-up, we found participants with higher baseline uric acid levels had a higher incidence of hypertension (p < 0.01). In stratified analysis by obesity, above relationship remained significant in nonobesity population (males: p < 0.05, females: p < 0.01) and became nonsignificant in obesity people. In stratified analysis by age, above positively correlation remained significant in middle-aged men (p < 0.05) and elderly women (p < 0.01). Restricted cubic spline revealed the dose-response relationship between SUA and hypertension; we also found that above relationship was much stronger in females.Conclusion: This study suggests that elevated SUA levels might be positively associated with an increased risk of hypertension in general Chinese adults.

show abstract

“…Blood pressure was measured 3 times at 30-s intervals, and the mean of the 3 measurements was used as the measured value. SBP was measured when the pulse sound first appeared (Korotkoff phase 1), and DBP was measured when the pulse sound disappeared (Korotkoff phase 5) [ 13 ].…”

Section: Methodsmentioning

confidence: 99%

Blood Pressure Trajectory and Its Influencing Factors in Chinese Adults: A Cohort Study with Long-Term Follow-Up

Yao

Wei

2022

Med Sci Monit

View full text Add to dashboard Cite

Background Few studies have been reported on the factors affecting the trajectory of blood pressure in Chinese adults. This study aimed to identify the pattern of blood pressure trajectories and analyze the factors affecting different trajectories. Material/Methods A total of 749 participants were included in this study from the China Health and Nutrition Survey (CHNS) database, collected between 1989 and 2006, and were followed up until 2015. A group-based trajectory model was used to identify similar development trajectories of blood pressure levels. Univariate and multivariate logistic regression analysis was used to explore the influencing factors of blood pressure trajectories. Results Three systolic (SBP) and diastolic blood pressure (DBP) trajectory groups were identified: Group 1, “low initial blood pressure and slight rise” (SBP, n=267, 35.65%); Group 2, “low initial blood pressure and moderate rise” (SBP, n=375, 50.07%); and Group 3, “high initial blood pressure and high rise” (SBP, n=107, 14.29%). In the SBP trajectory groups, age ≥40 years, male sex, body mass index (BMI) ≥24 kg/m 2 , and the eastern region of China were associated with a rapid rise and high baseline blood pressure ( P <0.01). In terms of DBP trajectory, male sex, BMI ≥24 kg/m 2 , and the eastern region of China were also related to the rapid rise and high baseline blood pressure, while age may not affect rise rate ( P <0.01). Conclusions Different blood pressure trajectories and related influencing factors may provide information for targeted interventions, especially for people with high initial blood pressure and high rise.

show abstract

Longitudinal association between physical activity and blood pressure, risk of hypertension among Chinese adults: China Health and Nutrition Survey 1991–2015

Cited by 25 publications

References 36 publications

Serum 25-hydroxyvitamin D might be negatively associated with hyperuricemia in U.S. adults: an analysis of the National Health and Nutrition Examination Survey 2007–2014

Serum 25-hydroxyvitamin D might be negatively associated with hyperuricemia in U.S. adults: an analysis of the National Health and Nutrition Examination Survey 2007–2014

Serum Uric Acid Might Be Positively Associated With Hypertension in Chinese Adults: An Analysis of the China Health and Nutrition Survey

Blood Pressure Trajectory and Its Influencing Factors in Chinese Adults: A Cohort Study with Long-Term Follow-Up

Contact Info

Product

Resources

About