Long term visual outcome of radiated uveal melanomas in eyes eligible for randomisation to enucleation versus brachytherapy.

Long-Term Surgical Outcome of Posterior Choroidal Melanoma Treated by Endoresection

“…Postoperatively, 40% of 20 eyes lost their vision (i.e., 3 with no light perception and 5 with enucleation) in our study, while loss of vision was 12.5% and 7.5%, respectively, in the studies by Kertes et al 10 and Damato et al 12 (which is worse than our results). According to current reports, the rate of blindness from choroidal melanoma after different methods of radiotherapy is 35.2% to 67%, 22,23,[25][26][27][28][29][30][31] which is consistent with our results.…”

Visual outcome, local tumour control, and eye preservation after106Ru/Rh brachytherapy for choroidal melanoma

“…The eyes with local recurrence were almost all enucleated with postoperative vision set at no light perception. In the literature, the risk factors for visual acuity loss are higher-age, poor initial visual acuity, increasing tumour height, proximity to fovea or optic disc, anterior tumour margin posterior to the equator, presence of subretinal fluid, and tumour recurrence [14Á/ 16,18,19,24,32,34,35] .…”

Dose De-Escalation With Gamma Knife Radiosurgery in the Treatment of Choroidal Melanoma

“…Current treatment strategies include resection, enucleation, brachytherapy and stereotactic radiation (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). Disease prognosis is variable, and the optimal treatment paradigm has yet to be defined.…”