Long-term survival and center volume for functionally single-ventricle congenital heart disease in England and Wales

Hospital resource utilization in a national cohort of functionally single ventricle patients undergoing surgical treatment

“…Survival data for a cohort encompassing the currently analyzed population were previously reported. 5

Figure 1 Flowchart of f-SV study population inclusion and exclusion steps and classifications. Identification of patients with and without HLHS, and classification into diagnosis types were done using an algorithm described previously 2 , 6 and further in the Appendix E1 .

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“… 1 Advances in surgical techniques, critical care, and follow-up improved the outcomes, which still remain less favorable than for other complex CHD. 2 , 3 , 4 , 5 , 6 …”

Risk Factors for Reintervention With Functionally Single-Ventricle Disease Undergoing Staged Palliation in England and Wales: A Retrospective Cohort Study

“…Our study aimed to evaluate population-based rates of, and risk factors for, cardiac reinterventions in children with functionally single-ventricle (f-SV) congenital heart disease. A retrospective cohort study was undertaken, including all children born in England and Wales with f-SV congenital heart disease 1 between 2000 and 2018 who underwent any initial or staged palliative procedures. 1 , 2 The National Congenital Heart Diseases Audit (registry) was used, with National Health Service Research Ethics Committee approval; the study dataset is available only on this basis.…”

“…A retrospective cohort study was undertaken, including all children born in England and Wales with f-SV congenital heart disease 1 between 2000 and 2018 who underwent any initial or staged palliative procedures. 1 , 2 The National Congenital Heart Diseases Audit (registry) was used, with National Health Service Research Ethics Committee approval; the study dataset is available only on this basis. Five-year survival, as ascertained in 2020, was 72.1% (95% CI, 70.6%–73.7%).…”

“…Five-year survival, as ascertained in 2020, was 72.1% (95% CI, 70.6%–73.7%). 1 The study outcome was any cardiac operation or interventional catheter undertaken in addition to the planned treatment pathway. The association between prespecified risk factors (see Table) and the cumulative incidence of additional procedures was investigated using multivariable Fine-Gray regression.…”