Long-term Subjective, Clinical, and Radiographic Outcome Evaluation of Meniscal Allograft Transplantation in the Knee

Vundelinckx, Bart; Vanlauwe, Johan; Bellemans, Johan

doi:10.1177/0363546514530092

Cited by 102 publications

(74 citation statements)

References 18 publications

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“…Using a Wilcoxon signed rank test to compare pre-operative Lysholm scores and Lysholm scores at final follow-up showed that there is a significant difference between these scores ( P < 0.005). However, it can be noted as shown in Figure 3 that patients who filled in the Lysholm questionnaire report less profit of MAT [5, 9, 11, 14, 17, 21, 23, 29, 40, 45, 46, 54, 57, 61, 62, 64, 66]. …”

Section: Resultsmentioning

confidence: 99%

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Meniscal allograft transplantation: a meta-analysis

Bruycker

Verdonk

2017

SICOT-J

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Purpose: This meta-analysis evaluates the mid- to long-term survival outcome of MAT (meniscal allograft transplantation). Potential prognosticators, with particular focus on chondral status and age of the patient at the time of transplantation, were also analysed. Study design: Meta-analysis. Methods: An online database search was performed using following search string: “meniscal allograft transplantation” and “outcome”. A total of 65 articles were analysed for a total of 3157 performed MAT with a mean follow-up of 5.4 years. Subjective and clinical data was analysed. Results: The subjective and objective results of 2977 patients (3157 allografts) were analysed; 70% were male, 30% were female. Thirty-eight percent received an isolated MAT. All other patients underwent at least one concomitant procedure. Lysholm, Knee injury and Osteoarthritis Outcome (KOOS), International Knee Documentation Committee (IKDC) and Visual Analogue Scale (VAS) scores were analysed. All scores showed a good patient satisfaction at long-term follow-up. The mean overall survival rate was 80.9%. Complication rates were comparable to standard meniscal repair surgery. There was a degenerative evolution in osteoarthritis with at least one grade in 1760 radiographically analysed patients. Concomitant procedures seem to have no effect on the outcome. Age at transplantation is a negative prognosticator. The body mass index (BMI) of the patient shows a slightly negative correlation with the outcome of MAT. Conclusions: MAT is a viable solution for the younger patient with chronic pain in the meniscectomised knee joint. The complications are not severe and comparable to meniscal repair. The overall failure rate at final follow-up is acceptable and the allograft heals well in most cases, but MAT cannot be seen as a definitive solution for post-meniscectomy pain. The correct approach to the chronic painful total meniscectomised knee joint thus requires consideration of all pathologies including alignment, stability, meniscal abnormality and cartilage degeneration. It requires possibly combined but appropriate action in that order.

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Section: Resultsmentioning

confidence: 99%

“…Less pain and swelling of the knee joint allow for more of their daily activities. However, pain seems to return over time, as patients who filled in the VAS-chart tend to report more pain (Figure 5) [4, 5, 15, 17, 21, 22, 27, 33–35, 37, 38, 47]. In the analysis of the KOOS-score, 12 papers were included.…”

Section: Resultsmentioning

confidence: 99%

Meniscal allograft transplantation: a meta-analysis

Bruycker

Verdonk

2017

SICOT-J

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“…Reoperations occur in 35% of patients, with 12% requiring conversion to total knee arthroplasty, based on a study of 49 patients with a mean follow-up of almost 13 years. 134 For others the outcome is more favorable, with significant improvement in pain and function in addition to generally well preserved joint spaces.…”

Section: Replacement Allograftmentioning

confidence: 99%

Magnetic Resonance Imaging of the Postoperative Meniscus

Boutin

Fritz²,

Marder

2014

Magnetic Resonance Imaging Clinics of North America

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“…Few large, long-term studies of meniscal allograft transplantation have been performed with the longest follow-up with 7 years, thereby making a modeling approach useful in identifying the optimal treatment over the long term [10,21,22]. Given the large cost discrepancy between the available procedures, a cost-effectiveness analysis is needed to determine whether the cost of meniscal allograft is outweighed by the ability to delay the need for TKA in this patient population.…”

Section: Introductionmentioning

confidence: 99%