Long-term outcomes (>2 years) of atrial fibrillation ablation using a multi-electrode ablation catheter in patients with paroxysmal atrial fibrillation

Abstract

There was a comparable and significant improvement in QoL post-ablation in patients who underwent ablation using PVAC catheter and conventional techniques.

Pulmonary vein isolation using multi-electrode radiofrequency vs conventional point-by-point radiofrequency ablation: A meta-analysis of randomized and non-randomized studies

“…On the other hand, nMARQ ® significantly increased the procedure time in the study of Wakili [24]. There was also a statistically significant reduction in total fluoroscopy time in most of the studies except for the studies by Beukema, Tivig (persistent AF subgroup), Looi, De Greef, Gal, and Rosso that no significant difference on total fluoroscopy times was observed between the 2 ablation strategies [12], [14], [15], [18], [20], [22]. Similar to procedure time, nMARQ ® significantly increased the fluoroscopy time in the study of Wakili [24].…”

“…[21] 58 years for the PVAC ® group and 62 years for the conventional group, all p < 0.05), gender (except for the study by Looi et al. [20] 55% male for the PVAC ® group and 74% male for the conventional group, p < 0.05), duration of AF or episode numbers, baseline ejection fraction, or left atrial diameter (except for the study by Khaykin et al. [19] p = 0.03, see Table 2), where available.…”

“…The PVAC ® catheter applying duty-cycled bipolar/unipolar radiofrequency energy was used as an active comparator in 11 studies whereas the nMARQ ® catheter was studied in studies by Wakili and Rosso [15], [24]. Blanking period was 1 month in studies by Bulava and Bittner [16], [17], 3 months in remaining studies [13], [14], [15], [18], [19], [20], [21], [22], [23], [24]. Arrhythmia recurrence was investigated using 12-lead electrocardiogram in the study by Looi [20], 24-h Holter recording in the studies of Gal and Rosso [15], [22], 7-day Holter recording in the studies by Bulava and Wakili [16], [24], 24- to 96-h Holter recording in the study by Bittner [17], 24–48-h Holter monitoring in the studies by Choo and Khaykin [13], [19], 24- to 168-h Holter monitoring and 1 week AF alarm monitoring in the study of Beukema [18], 7-day ECG external loop recorder in the study by Tivig [12], 72-h Holter recording in the study of McCready [21], 1- to 7-day Holter recording or event recording in the study by De Greef [14], and implantable cardiac monitor and dual chamber pacemaker in the study by Podd [23].…”

“…In each sensitivity analysis carried out using the one study out method, there remained no statistically significant difference in the impact of multi-electrode radiofrequency ablation on arrhythmia recurrence, except for the study of Looi et al. [20] (p = 0.048) (Online supplementary material 1 and 2). …”

Healthcare Utilization and Quality of Life Improvement after Ablation for Paroxysmal AF in Younger and Older Patients

“…In the AF population, QoL improves with treatment and improvement is associated with maintenance of NSR . For older patients, QoL has been shown to significantly decrease with increasing age and AF ablation has been shown to significantly improve the QoL in AF patients . Quantification of symptom improvement through assessment of health‐related QoL is a critical component in evaluating patient outcomes and clinical effectiveness of AF ablation .…”