Long-term outcome for lymph node-positive prostate cancer

Abstract

Although the number of men with lymph node-positive prostate cancer has declined, it is still significant and the challenge remains on how best to treat these patients. Only long-term follow-up can give a true indication of the outcome in prostate cancer. We evaluated our experience in treating lymph node-positive prostate cancer with a median follow-up of 10.2 years. The overall 5-year survival was 78% and the 10-year survival was 56%. Length of tumor control depends on the type of treatment given. Adding androgen ablation improves the duration of control dramatically, although optimal timing is still uncertain.

The Spontaneous Remission of Recurrent Lymph Node Metastatic Prostate Cancer With Lowering Serum Prostate-Specific Antigen Level

“…In the current case, hormone therapy was selected as the initial treatment because lymph node metastasis was present at the time of diagnosis. Swanson et al reported the five-year and 10-year survival rates of lymph node-positive prostate cancer were 78% and 56%, respectively [ 8 ]. Our patient is still alive 25 years after the initial diagnosis and is not currently receiving any treatment.…”