Long-term outcome for infants and children with sacrococcygeal teratoma: A report from the childrens cancer group

Rescorla, Frederick J.; Sawin, Robert S.; Coran, Arnold G.; Dillon, Peter W.; Azizkhan, Richard G.

doi:10.1016/s0022-3468(98)90426-2

Cited by 194 publications

(158 citation statements)

References 28 publications

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“…As per Rescorla et al, all pa ents presen ng a er the age of one year had malignant tumours 12 . Gabra et al also reported that 71% of their pa ents presen ng beyond neonatal period were malignant 13. These interpreta ons are consistent with our results, two pa ents who presented beyond 1 year of age had >50% immature ssue (malignant component) on histology.…”

Section: Resultsmentioning

confidence: 66%

Sacrococcygeal Teratoma: Experience with 36 Patients in a Teritiary Care Hospital

Kundal

Jadhav

Gupta

et al. 2015

J. Nepal Paedtr. Soc.

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Introduction: Sacrococcygeal teratomas (SCT) are the most common solid tumours in the neonatal period, originate from embryonic totipotent cells. Most of them are benign however some that present later in life and have major intra-pelvic component have greater malignant potential. Complete surgical excision provides an excellent prognosis. The aim of this study was to describe the clinical profile, age of presentation, sex distribution, diagnostic evaluation and management of children with a histological confirmed diagnosis of sacrococcygeal teratoma.Material and Methods: Patients with histological diagnosis of sacrococcygeal teratoma during a period from January 2011 to December 2012 were included in this retrospective study. Data collected included age of presentation, sex distribution, symptoms, associated anomalies, diagnostic evaluation, operative approach technique employed, tumour histology, operative complications and outcome.Results: Thirty six patients with diagnosis of sacrococcygeal teratoma were included in the study. Of these children, 58.33% were females and 41.66% were males. The median age at presentation was four days. 69.44% of patients presented during the neonatal period. 77.77% of patients presented with sacrococcygeal mass followed by lower abdominal mass in 11.11%. The tumour was resected by sacral approach in 27 patients and abdomino sacral approach in nine patients. Tumour was resectable in 34 patients and two had incomplete resection. Follow up duration varied from six months to 24 months.Conclusion: Sacrococcygeal teratomas represent a group of benign and malignant lesions of children. Neonates present with benign disease and aggressive lesions are seen as age progresses. Overall survival of SCT is high.J Nepal Paediatr Soc 2015;35(1):89-93

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Section: Resultsmentioning

confidence: 66%

Sacrococcygeal Teratoma: Experience with 36 Patients in a Teritiary Care Hospital

Kundal

Jadhav

Gupta

et al. 2015

J. Nepal Paedtr. Soc.

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“…Teratomas are the tumour which consists of the tissues that arise from embryonic ectoderm, mesoderm and endoderm. Common locations of teratomas in children are sacroccocygeal, gonadal, mediastinal, and retroperitoneal [1][2][3][4][5]. Teratomas may also occur at very unusual locations and are intra-peritoneal teratomas arising from mesentery and mesocolon, gastric teratoma, spinal teratoma, teratoma occurring at cervical region, intra-cranial teratomas occurring at medulla oblongata, teratoma occurring at liver and kidney [6-10].…”

Section: Discussionmentioning

confidence: 99%

Mature Teratoma at Left Lumbar Region in an Infant: A Case Report

Ghritlaharey¹

2016

JCDR

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“…Na falha destes objetivos, a recorrência é a regra. No paciente com teratoma maduro o único tratamento preconizado é o cirúr-gico, possuindo uma taxa de recidiva em torno de 4% (seguimento de 39 meses), impondo seguimento de no mínimo 3 anos 1,22 . Nos casos de teratoma imaturo, o desconhecimento da probabilidade de sua malignidade, não permitiu estabelecer como rotina o tratamento adjuvante de quimioterapia e radioterapia 6,8 .…”

Section: Discussionunclassified

Teratoma sacrococcígeo: relato de três casos

Falavigna

Gandara

Ferraz

et al. 2004

Arq. Neuro-Psiquiatr.

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RESUMO -Os tumores de células germinativas são derivados da célula germinativa primordial de localização gonadal ou extragonadal. O teratoma é um dos seus constituintes, cuja localização extragonadal mais comum é a região sacrococcígea, independente da sua classificação histopatológica em benignos ou malignos. Descrevemos três casos de teratomas sacrococcígeos e enfatizamos aspectos do diagnóstico, técnica cirúrgica e manejo complementar. PALAVRAS-CHAVE: teratoma, sacrococcígeo, neoplasias da medula espinhal. Sacrococcigeal teratoma: report of three casesABSTRACT -Germ cell tumors are originated from the primary stem cell located either in or outside the gonadal system. Teratomas are the major group, with the sacrococcygeal location being the most common extragonadal site, independent they are benign or malignant. We describe three cases of sacrococcygeal teratoma and emphasize aspects of diagnosis, surgical techniques and complementary approaches. . O teratoma apresenta implantação gonadal ou extragonadal. A região sacrococcígea é a localização extragonadal mais comum, podendo a lesão ser do tipo sólida, multicística ou formada por grande cisto único 3,4 . Nessa região encontram-se 39% a 60% dos teratomas, sejam eles benignos ou malignos [5][6][7][8][9][10]

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Long-term outcome for infants and children with sacrococcygeal teratoma: A report from the childrens cancer group

Cited by 194 publications

References 28 publications

Sacrococcygeal Teratoma: Experience with 36 Patients in a Teritiary Care Hospital

Sacrococcygeal Teratoma: Experience with 36 Patients in a Teritiary Care Hospital

Mature Teratoma at Left Lumbar Region in an Infant: A Case Report

Teratoma sacrococcígeo: relato de três casos

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