Long-Term Oncologic Outcomes After Radiofrequency Ablation for T1 Renal Cell Carcinoma

Psutka, Sarah P.; Feldman, Adam S.; McDougal, W. Scott; McGovern, Francis J.; Müeller, Peter R.; Gervais, Debra A.

doi:10.1016/j.eururo.2012.08.062

Cited by 289 publications

(187 citation statements)

References 33 publications

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“…Due to the increasing number of diagnostic procedures, nowadays most renal tumors are detected incidentally at an early stage [1]. The currently available intermediate-and long-term data demonstrate a high rate of oncologic success of image-guided percutaneous RFA with 5-year cancer-specific survival rates of up to 100 % [2,3]. In the latest controlled trials, percutaneous RFA and nephrectomy show comparable survival rates.…”

Section: Introductionmentioning

confidence: 99%

Treatment Failure After Image-Guided Percutaneous Radiofrequency Ablation (RFA) of Renal Tumors – A Systematic Review with Description of Type, Frequency, Risk Factors and Management

Vollherbst

Bertheau

Kauczor

et al. 2016

Fortschr Röntgenstr

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Section: Introductionmentioning

confidence: 99%

Treatment Failure After Image-Guided Percutaneous Radiofrequency Ablation (RFA) of Renal Tumors – A Systematic Review with Description of Type, Frequency, Risk Factors and Management

Vollherbst

Bertheau

Kauczor

et al. 2016

Fortschr Röntgenstr

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“…The estimated 5-year recurrence-free survival was 93.3 %, with a complication rate of 8.8 % of which 3.8 % were considered major. Psutka et al [39] studied the long-term oncological outcomes for patients, with T1 renal cell cancers treated by RFA. This group had 185 patients, who were further categorized as T1a and T1b tumours.…”

Section: Oncological Outcome Of Rfamentioning

confidence: 99%

Non-Surgical Ablative Therapy for Management of Small Renal Masses—Current Status and Future Trends

Farrag

Sriprasad

2016

Indian J Surg Oncol

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A large number of small renal masses (SRMs) with size less than 4 cm are being identified due to advances in diagnostic imaging. As the natural history of these tumours remains unknown, there is no reliable way to predict their behaviour or future growth. Although, partial nephrectomy is the gold standard for treatment of these tumours, ablative non-surgical therapies such as cryoablation and radiofrequency ablation provide a less invasive option of treatment with comparable oncological outcomes. In this systematic review, the principle, indications, methods of treatment, oncological control, complication and renal function of ablative therapies are critically reviewed. Cryotherapy utilizes the principle of inducing tissue destruction by freezing and thawing using argon and helium gasses, respectively. Radiofrequency ablation (RFA) works on the principle of tissue heating. Ablative treatments are particularly useful in the elderly patients, those with comorbidities or in patients with SRMs in solitary kidneys or renal impairment. Ablative therapies have less procedurerelated complications and have promising medium-term oncological outcome. Longer-term results are accumulating. Cryotherapy may be a better modality for oncological control than RFA. Ablative therapy has emerged as a viable treatment options for SRMs with recurrence free survival rates approaching that of extirpative surgery. However, there is no consensus in the literature on the best selection criteria and this needs further refinement. Prospective long-term data with regards to oncological control is still needed

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“…RFA causes less deterioration of renal function than partial nephrectomy with similar oncological outcomes [29,30,31,32]. Psutka et al [33] in a study of 185 patients with Stage I renal tumour reported a 5-year recurrence-free survival of 96.1%. Cryoablation causes direct cellular damage as a result of osmotic cellular dehydration and intracellular formation of ice [34,35,36].…”

Section: Accuracy and Reproducibility Of Quantitative Cardiac Mrimentioning

confidence: 99%

Friday 14 October 2016

2016

J Med Imag Rad Onc

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Purpose: Varicocele (abnormal dilatation of the pampiniform plexus secondary to a defect in the venous renospermatic system) is a relatively common condition, affecting 8-23% of young healthy males (1). Though often benign, it may create problems (significant pain in 14% or male factor infertility) that warrant intervention (1). Options for treatment are broadly classified into surgical or radiological (2). We aimed to determine the efficacy of radiological embolisation for the treatment of varicoceles by a single interventional radiology unit. Materials and methods: A retrospective review of all varicocele embolisation procedures performed by the interventional radiology unit at Austin Hospital (Melbourne) for the period of July 2005 to June 2015 was performed. Records and details (demographics, side, indication, duration, length of coil, complications) were obtained from electronic databases. Follow-up data was collected from the referring urologists. Results: A total of 131 varicocele embolisation procedures were performed. The majority of patients 105/131 (80%) were less than 40 years of age. Major indications were symptomatic pain (69%) or subfertility (10%). Laterality was 127/131 (97%) for left and 4/131 (3.1%) for bilateral varicoceles. Total coil length ranged from 18 to 38 mm. Procedure lengths averaged at 45mins. Complication rate was 6.1%, and mostly minor and not resulting in procedural abandonment. Complete follow-up data was obtained for 83patients only. Of these, recurrence occurred in only five patients (6.0%). Conclusions: Our study demonstrates that radiological embolisation is an effective modality for the treatment of varicoceles. Our single centre experience demonstrates comparable complication and recurrence rates of radiological embolisation versus the surgical treatment options (3). Given radiological embolisation is a day procedure with a reasonably short procedure time; our findings make it an effective option comparable to surgery. Objective / Introduction: Radiography of the immature skeleton is complex for junior doctors and students due to physes and ossification centers. Knowledge of normal radiographic characteristics is important to interpretation, which form the majority of xray studies of the paediatric population. Books and image based resources such as Keats Atlas of Normal Variants are cumbersome as an introductory resource, and a video/timelapse approach to normal skeletal development would condense the knowledge to a more accessible form. Project objective is to improve JMO proficiency in reading paediatric radiographs, including familiarity with the order of appearance of ossification centers, and improved fracture detection accuracy. Methods and materials:To demonstrate feasibility, a test timelapse was completed for the pelvis and proximal femur for 0-10 years of age. Anonymised radiographs were obtained from the local radiology department PACS. Images were aligned and stacked in a video editor, and annotated the order of appearance of ossification centres and physeal...

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Long-Term Oncologic Outcomes After Radiofrequency Ablation for T1 Renal Cell Carcinoma

Cited by 289 publications

References 33 publications

Treatment Failure After Image-Guided Percutaneous Radiofrequency Ablation (RFA) of Renal Tumors – A Systematic Review with Description of Type, Frequency, Risk Factors and Management

Treatment Failure After Image-Guided Percutaneous Radiofrequency Ablation (RFA) of Renal Tumors – A Systematic Review with Description of Type, Frequency, Risk Factors and Management

Non-Surgical Ablative Therapy for Management of Small Renal Masses—Current Status and Future Trends

Friday 14 October 2016

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