“…l-1,2,3,6-tetrahydropyridine (MPTP) intoxication to produce Parkinson's disease-like lesions of the nigro-striatal dopaminergic system (PD). Previous reports derived from these experiments concerned specifically behavioural data Bashir et al, 2012;Freund et al, 2006Freund et al, , 2009Hamadjida et al, 2012;Hoogewoud et al, 2013;Kaeser et al, 2010Kaeser et al, , 2011Wyss et al, 2013), imaging of dopaminergic function or tracing data on the CS tract (Beaud et al, 2008;Freund et al, 2007), the rubrospinal projection (Wannier-Morino et al, 2008) or callosal projection . In the present study, this rich collection of monkeys subjected to one of these pathologies (MCI, SCI, PD; n = 13) was analysed here in order to compare their corticobulbar projections to PMRF with that of a cohort of intact monkeys (n = 7) recently reported .…”