Long-term major adverse cardiovascular events and quality of life after coronary angiography in elderly patients with acute coronary syndrome

Sigurjónsdóttir, Rúna; Barywani, Salim Bary; Albertsson, Per; Fu, Michael

doi:10.1016/j.ijcard.2016.07.237

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…This worsening of the cardiac contractile function is one of the prognostic factors for bad prognosis. The risk increases at least 3 times [17,20], as found in our results. Mild and severe left ventricular dysfunctions are associated with higher risk in patients with AMI, especially in combination with co-morbidities [21].…”

Section: Discussionsupporting

confidence: 85%

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One-Year Cardiovascular Outcome in Patients on Clopidogrel Anti-Platelet Therapy After Acute Myocardial Infarction

et al. 2018

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The aim of this study was to determine the risk factors in patients on clopidogrel anti-platelet therapy after acute myocardial infarction, for cardiovascular mortality, re-hospitalization and admission to emergency care unit. We followed 175 patients on dual antiplatelet therapy, with clopidogrel and acetylsalicylic acid, for 1 year after acute myocardial infarction, both STEMI and NSTEMI. Beside demographic and clinical characteristics, genetic ABCB1, CYP2C19 and CYP2C9 profile was analyzed using Cox-regression analysis. End-points used were: mortality, re-hospitalization and emergency care visits, all related to cardiovascular system. During the accrual and follow-up period, 8 patients (4.6%) died, mostly as a direct consequence of an acute myocardial infarction. Re-hospitalization was needed in 27 patients (15.4%), in nine patients (33.3%) with the diagnosis of re-infarction. Thirty-two patients (18.3%) were admitted to emergency care unit due to cardiovascular causes, up to 15 times during the follow-up. NSTEMI was an independent predictor of all three events registered (mortality OR=7.4, p<0.05; re-hospitalization OR=2.8, p<0.05); emergency care visit OR=2.4, p<0.05). Other significant predictors were related to kidney function (urea and creatinine level, creatinine clearance), co-morbidities such as arterial hypertension and decreased left ventricular ejection fraction, as well as clopidogrel dosing regimen. As a conclusion, it may be suggested that one of the most significant predictors of cardiovascular events (mortality, re-hospitalization and emergency care visits) is NSTEMI. Besides, clopidogrel administration according to up-to-date guidelines, with high loading doses and initial doubled maintenance doses, improves 1-year prognosis in patients with AMI.

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Section: Discussionsupporting

confidence: 85%

“…Hyperlipidemia is a known risk factor for ACS and for the worse prognosis after AMI [16]. Our results have shown that high LDL favored good prognosis, as found in similar studies [17]. This may be due to the therapy with statins.…”

Section: Discussionsupporting

confidence: 85%

One-Year Cardiovascular Outcome in Patients on Clopidogrel Anti-Platelet Therapy After Acute Myocardial Infarction

et al. 2018

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“…ACS, regardless of the reason for its onset, impacts a patient’s physical and psychological life, with repercussions on a subject’s general health and quality of life [ 9 , 12 , 13 ]. However, as indicated above, not many studies have analyzes the impact of physical limitations on psychological aspects such as quality of life, anxiety, depression, or social functioning, and even less on post-traumatic growth.…”

Section: Discussionmentioning

confidence: 99%

“…Patients often face limitations imposed by the disease, but there are important psychological consequences that affect their quality of life [ 7 ]. These factors need to be considered because they influence adherence to treatments and patients’ quality of life [ 6 , 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Psychological State after an Acute Coronary Syndrome: Impact of Physical Limitations

Rosa

León-Zarceño

Giglio

et al. 2021

IJERPH

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The aim of this study was to investigate how physical limitations after ACS influence patients’ quality of life and health perception. This was a longitudinal clinical study. We recruited 146 patients diagnosed with ACS. The patients performed a stress test (Bruce’s protocol) for the evaluation of physical limitations and were classified according to the test result: without physical limitations (more than 10 METS), with some physical limitations (7 to 9 METS), and with high physical limitations (less than 6 METS). Significant differences were found between the three groups immediately after the diagnosis of ACS and after a period of three months, regarding health perception, anxiety, depression, sexual relationships, distress, and adjustment to disease. These differences resulted larger between the group with less limitations and the group with higher limitations. After 3 months, however, there was an overall improvement in all variables. In conclusion, physical limitations after ACS seem to influence perceived quality of life determined by measuring general health, vitality, total adaptation, emotional role, social adaptation, depression, and anxiety. Therefore, the highest the physical limitations, the poorer the psychological conditions and vice versa, even 3 months after ACS diagnosis.

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Prognostic impact of left ventricular ejection fraction in patients with electrical storm

Müller¹,

Behnes²,

Ellguth³

et al. 2019

J Interv Card Electrophysiol

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Long-term major adverse cardiovascular events and quality of life after coronary angiography in elderly patients with acute coronary syndrome

Cited by 4 publications

References 19 publications

One-Year Cardiovascular Outcome in Patients on Clopidogrel Anti-Platelet Therapy After Acute Myocardial Infarction

One-Year Cardiovascular Outcome in Patients on Clopidogrel Anti-Platelet Therapy After Acute Myocardial Infarction

Psychological State after an Acute Coronary Syndrome: Impact of Physical Limitations

Prognostic impact of left ventricular ejection fraction in patients with electrical storm

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