Long-Term Follow-Up of Patients With Polycystic Ovary Syndrome After Laparoscopic Ovarian Drilling: Endocrine and Ultrasonographic Outcomes

Amer, Saad; Banu, Zeenat; Li, T. C.; Cooke, I. D.

doi:10.1097/01.ogx.0000058686.18516.5d

Cited by 18 publications

(27 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, several explanations can be made: (1) A single drilling destroys an average of 0.4 mL of stromal ovarian tissue 22 and eight drills result in a reduction of approximately 3.2 mL; (2) normalised ovarian function after drilling. 23 The possibility that this reduction in summed ovarian volume is due to either inter-or intra-observer variability is excluded because the same person (first author) performed the sonographic examination with the same machine at initial examination and at the three months follow up examination.…”

Section: Discussionmentioning

confidence: 99%

Hormonal and sonographic assessment of ovarian reserve before and after laparoscopic ovarian drilling in polycystic ovary syndrome

Kandil

Selim

2005

BJOG

View full text Add to dashboard Cite

This prospective observational study aimed to assess ovarian reserve after three different methods for induction of ovulation in 60 women between 30 and 40 years old with polycystic ovary syndrome. Women were equally divided into three groups. Group I included women who responded to clomiphene citrate. Women enrolled in groups II and III were subjected to either unilateral or bilateral ovarian drilling, respectively. Ovarian reserve testing was performed once before and three months after treatment. Basal serum inhibin B level showed a significant decrease after bilateral drilling compared with predrilling level (53.8 F 13.5 vs 46.3 F 6.2 pg/mL; P ¼ 0.031). The antral follicle counts and summed ovarian volume showed a significant decrease after bilateral drilling (16.5 F 1.3 vs 14.9 F 2

show abstract

Section: Discussionmentioning

confidence: 99%

Hormonal and sonographic assessment of ovarian reserve before and after laparoscopic ovarian drilling in polycystic ovary syndrome

Kandil

Selim

2005

BJOG

View full text Add to dashboard Cite

show abstract

“…These patients were managed by ovarian drilling which also reduces the need of gonadotropin therapy and complications associated with it. 12 The next common laparoscopic finding in infertile women seen is endometriotic cyst. We report an incidence of 46 (13.81%) women requiring endometriotic cystectomy.…”

Section: Discussionmentioning

confidence: 99%

Role of hysterolaparoscopy for the evaluation of primary infertility: An experience from a tertiary care hospital

Pande

Dora

Pradhan

et al. 2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

INTRODUCTIONInfertility is one of the most common problem for which couple seeks medical attention. It is seen almost in 10-15% of the reproductive couple.1 Though there are various tests available for the evaluation of the patients with infertility, for the complete evaluation of pelvic pathology hysterolaparoscopy became the gold standard over the years. Ovulatory dysfunction accounts for 21% to 32%, tubal factor 14% to 26%, unexplained 8% to 30% and endometriosis accounts 4% to 6% of female infertility.2-4 Hysterolaparoscopy gives detailed and magnified view of uterine, adenexal, peritoneal and other intra-abdominal pathology. Consequently, milder degree of distal fimbrial pathology, endometriosis, and pelvic adhesions can be diagnosed and treated at the same time which was missed during a routine trans vaginal ultrasonography. The main objective of the study was to assess the role of diagnostic hysterolaparoscopy in the diagnosis and treatment of primary infertility patients. METHODSThis was a hospital based retrospective observational study. Medical records of all cases of primary infertility were retrieved and analyzed. This study was conducted ABSTRACT Background: Infertility is one of the most common problem for which couple seeks medical attention. The main objective of the study was to assess the role of diagnostic hysterolaparoscopy in the diagnosis and treatment of primary infertility patients. Methods: For this retrospective study, patient with the diagnosis of primary infertility were recruited. Patients admitted between the periods 2014 to 2016 were included. Pertinent data related to infertility were collected from the case records and entered in predesigned performa. Results: Patients with primary infertility 246 (82%) diagnosed to have pelvic pathology. The most common cause of infertility was ovarian 122 (36.63%), Uterine 66 (19.82%), tubal 84 (25.22%) and unexplained infertility in 103 (30.93%) women. Patients with PCOS 76 (22.82%) and endometriosis 46 (13.81%) treated with drilling and endometriotic cystectomy. In 32 (9.60%) of patients hysteroscopic cannulation was done. For distal tubal blockage fimbrioplasty was performed in 38 (11.41%) of women. Pelvic adhesions diagnosed in 26 (7.80%) women. patients diagnosed with uterine septum 42 (12.61%) required hysteroscopic septal resection. During the evaluation of infertility 70 (21%) of women diagnosed to have incidental pelvic pathology treated according to pathology. Conclusions: Hysterolaparoscopy is emerging as a valuable technique for complete assessment of female infertility and also helps in treatment according to the cause.

show abstract

“…In a long-term follow-up study, Gjønnaess ascertained that ovulation still occurred in 23 out of 31 women (74%), 10 to 20 years after LOD 27 Amer et al concluded that LOD is associated with a sustained improvement in menstrual regularity and reproductive function in about one-third of cases and that the beneficial decrease in LH/ FSH ratio, LH and testosterone levels and the reduction in ovarian volume lasted up to nine years in most patients. 17,28 In a questionnaire based study of 168 women 8 to 12 years after being randomized to receive LOD or ovulation induction with gonadotrophins, 54% of the LOD-treated women had regular menstrual cycles and had an increased chance of having a second child. 29 Long-term follow-up of our cohort confirm that improvement in ovulation is sustained over time as demonstrated by the 52% of women that still had regular menstrual cycles after three to nine years.…”

Section: Discussionmentioning

confidence: 99%

Short and Long-Term Efficacy of Laparoscopic Ovarian Diathermy in Women with Polycystic Ovary Syndrome

Luz¹,

Barros²,

Aguiar³

et al. 2016

Acta Med Port

View full text Add to dashboard Cite

Introduction:Polycystic ovary syndrome is the most frequent cause of anovulatory infertility and management involves a multistep approach. Laparoscopic ovarian diathermy is accepted as a second-line treatment of patients who failed to respond to clomiphene citrate. The aims of this study were to determine the efficacy of this technique at short and long-term and to perform an analysis of predictive factors of spontaneous pregnancy. Material and Methods:This retrospective study involved 76 women who underwent laparoscopic ovarian diathermy between 2004 and 2013 in a university hospital. Main outcomes were cycle regularity and pregnancy. Short-term outcomes recorded during followup in our centre were reviewed and long-term outcomes were evaluated by a telephone interview to all women whose surgery was undertaken more than three years ago. Clinical and biochemical data were analysed as predictive factors of spontaneous conception in patients without other infertility factors.Results: Menstrual cycle regularity was initially achieved in 53 (70%) women and in the long-term follow-up subgroup, 52% (12/23) had regular periods. In general, 53 (70%) women conceived and 77 pregnancies were achieved, 60% of which were spontaneous. The only prognostic factor found to be significantly associated with spontaneous conception was a shorter duration of infertility (< 3 years) (p < 0.05). Discussion: Laparoscopic ovarian diathermy showed pregnancy rates comparable to other ovulation induction treatments with the advantage of having a long lasting beneficial effect in menstrual regularity and fertility. Conclusion: Laparoscopic ovarian diathermy is a safe and effective treatment option for anovulatory infertility in women with polycystic ovary syndrome.

show abstract

Long-Term Follow-Up of Patients With Polycystic Ovary Syndrome After Laparoscopic Ovarian Drilling: Endocrine and Ultrasonographic Outcomes

Cited by 18 publications

References 0 publications

Hormonal and sonographic assessment of ovarian reserve before and after laparoscopic ovarian drilling in polycystic ovary syndrome

Hormonal and sonographic assessment of ovarian reserve before and after laparoscopic ovarian drilling in polycystic ovary syndrome

Role of hysterolaparoscopy for the evaluation of primary infertility: An experience from a tertiary care hospital

Short and Long-Term Efficacy of Laparoscopic Ovarian Diathermy in Women with Polycystic Ovary Syndrome

Contact Info

Product

Resources

About