Long-term complications associated with breast-conservation surgery and radiotherapy

Abstract

Breast-conservation surgery plus radiotherapy was associated with grade 2 or higher complications in only 9.9% of patients. Half of these complications were attributable to axillary dissection, it is hoped that lower complication rates can be achieved with sentinel lymph node biopsy. Breast-conservation surgery and radiotherapy is associated with grade 2 or greater complications in only 9.9% of patients. Nearly half of these complications are attributable to axillary dissection.

Prone versus supine positioning for whole and partial-breast radiotherapy: A comparison of non-target tissue dosimetry

“…The START trial suggests that 40% of women experience chest-wall discomfort at 10 years post-RT (33), whilst the incidence of rib-fracture following WBI is reported to be 0.3-2.2% (34,35). A recent study of external-beam-accelerated-PBI found the incidence of chest-wall pain and rib fracture to relate to the volume of chest-wall receiving 35Gy or more (based on 38.5Gy/10 fractions 5 days (36)).…”

Outcome of axillary staging in early breast cancer: a meta-analysis

“…The time course of lymphedema after SNB is not well documented. Considering this, it is possible that longer follow up of patients included in our analysis could result in a greater difference between groups in the risk of development of lymphoedema [15].…”

Distribution of Early-Stage Lymphedema and Risk Factors in Postoperative Patients with Breast Cancer: A Hospital Based Study

“…28 In many studies, the LN number dissected was found to increase the lymphedema risk. 17,29,30 It is reported that the lymphedema frequency, which is recommended to be performed in axilla-negative cases today compared to AD.…”