Long-Term Clinical Outcomes After Filter Protection During Percutaneous Coronary Intervention in Patients With Attenuated Plaque　― 1-Year Follow up of the VAMPIRE 3 (Vacuum Aspiration Thrombus Reemoval 3) Trial ―

Abstract

PCI, and are associated with poor clinical outcomes, including greater infarct size and mortality. 1,2 PCIinduced distal embolization of atherosclerotic debris and thrombus was believed to cause impaired myocardial perfusion and adverse clinical outcomes. Thrombectomy and P rimary percutaneous coronary intervention (PCI) is the most common and widely accepted effective strategy for treating ST-segment elevation myocardial infarction (STEMI). However, reduced coronary flow and myocardial perfusion sometimes occur after otherwise

Prediction of Slow-Flow Phenomenon After Stent Implantation Using Near-Infrared Spectroscopy in Patients With Acute and Chronic Coronary Syndrome

“…11 Filtrap TM reduced the incidence of slow-flow phenomenon and in-hospital adverse clinical events, 24 but failed to improve 1-year cardiac mortality rates or the incidence of MI. 25 IVUS is limited in ability to distinguish between thrombus and lipid-rich plaque that is causing the slow-flow phenomenon because both can show echo attenuation. NIRS can depict lipid-rich plaque by displaying its metric value, but it does not address the issue of intra-and interobserver variability of eye-ball judgment, 26 which is undoubtedly a factor in the analysis of IVUS and optical coherence tomography (OCT).…”

Excimer laser coronary angioplasty versus manual aspiration thrombectomy in patients with ST-segment elevation myocardial infarction: analyzed by nuclear scintigraphy

“…In recent decades, several randomized controlled trials using manual aspiration thrombectomy or distal protection devices have failed to verify the clinical superiority of these devices in patients with ACS [4,[19][20][21][22]. Moreover, endpoints using cardiac magnetic resonance imaging or nuclear scintigraphy did not show any advantage of these devices in terms of MI size and improvement of LVEF [23].…”

Intravascular Imaging for Percutaneous Coronary Intervention Guidance and Optimization: The Evidence for Improved Patient Outcomes

“…19 At 1 year, MACEs occurred in 12.2% of the distal protection vs 3.1% of the conventional treatment group (P ¼ .029), driven by a higher risk of TVR (11.2% vs 2.1%; P ¼ .018). 20…”