Abstract:The objective of this study was to determine the safety and efficacy of (32)P beta-brachytherapy in totally occlusive in-stent restenosis (ISR). Patients with occlusive ISR were generally excluded from the randomized clinical trials on intracoronary brachytherapy (utilizing either gamma- or beta-sources) that have shown reductions in restenosis rate and need for revascularization procedures. We analyzed short- and long-term effects of (32)P beta-brachytherapy (20 Gy) in 27 patients (28 lesions) with occlusive … Show more
“…However, the external validity of these studies was, to some extent, limited by the exclusion of patients with occlusive lesions. In our previous analysis [19], occlusive ISR treated with 32 P IRT was associated with a higher incidence of MACE and angiographic restenosis at 7-month follow-up than nonocclusive ISR was. In this study, occlusive ISR proved to be a strong independent predictor of angiographic failure at follow-up.…”
“…However, the external validity of these studies was, to some extent, limited by the exclusion of patients with occlusive lesions. In our previous analysis [19], occlusive ISR treated with 32 P IRT was associated with a higher incidence of MACE and angiographic restenosis at 7-month follow-up than nonocclusive ISR was. In this study, occlusive ISR proved to be a strong independent predictor of angiographic failure at follow-up.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.