Long-term appraisal of coronary bypass operations in familial hypercholesterolemia

Takahashi, Tetsuya; Nakano, Susumu; Shimazaki, Yasuhisa; Kaneko, M; Hirata, Nobuaki; Nakamura, Tadashi; Matsuzawa, Yūji; Kitamura, Soichiro; Matsuda, Hikaru

doi:10.1016/0003-4975(93)90887-n

Cited by 13 publications

(15 citation statements)

References 16 publications

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“…Previous reports showed the advantage of arterial grafts to venous grafts in adults. 7 Takahashi et al reported that the patency rate of internal mammary artery grafts to the LAD was significantly higher than the venous ones. 7 IMA grafts have better long-term patency, 8 which can be important in children undergoing CABG, although excellent results have been reported regarding the patency and growth in saphenous vein grafts.…”

Section: Discussionmentioning

confidence: 99%

Triple coronary artery bypass graft in a 10-year-old child with familial hypercholesterolemia

Nemati

Astaneh

Joubeh

2009

Gen Thorac Cardiovasc Surg

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Familial hypercholesterolemia is a genetic disorder caused by a mutation in the low density lipoprotein (LDL) receptor gene. The homozygous type of the disease is rare and causes tendon xanthomas and coronary artery disease during the early years of life. Herein we present a 10-year-old child with familial hypercholesterolemia who had three-vessel disease and was a candidate for liver transplantation. To the best of our knowledge, he is one of the youngest such patients reported in the English-language literature who underwent coronary artery bypass surgery.

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Section: Discussionmentioning

confidence: 99%

Triple coronary artery bypass graft in a 10-year-old child with familial hypercholesterolemia

Nemati

Astaneh

Joubeh

2009

Gen Thorac Cardiovasc Surg

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“…Appraisal of coronary bypass operations in FH had a cardiac free event of 60% at 5 and 10 years for homozygotes compared to 87% and 73% for heterozygotes which has been comparable with patients without FH who were randomly age-matched that underwent CABG during the same time frame [23]. …”

Section: Discussionmentioning

confidence: 99%

Heterozygous Familial Hypercholesterolemia With APOE Haplotype: A Prospective Harbinger of a Catastrophic Cardiovascular Event

2017

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We report a very young man with heterozygous familial hypercholesterolemia (FH) with APOE haplotype and a significant cardiac family history who underwent cardiac catheterization for intermittent episodes of exertional dyspnea and was noted to have a severe triple vessel coronary artery disease (CAD). He underwent coronary artery bypass graft (CABG) surgery which was uneventful. He was discharged on antiplatelet, beta blocker, nitrate, and statin. On routine health maintenance evaluation, he had no cardiac complaints and had been tolerating well his activities of daily living.

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“…In terms of actuarial survival and freedom from symptoms arterial grafts are found to be superior in patients with familial hypercholesterolemia [4]. However there is no additional benefit in using multiple arterial grafts [5].…”

Section: Commentmentioning

confidence: 98%

Coronary artery bypass surgery in the second decade of life

Bhat

Peer

2010

Indian J Thorac Cardiovasc Surg

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Familial hypercholesterolemia (FH) is an autosomal dominant disorder of lipid metabolism. These patients develop coronary artery disease in the second or third decade of life, but patients requiring a coronary artery bypass in the second decade of life is rare. We report our experience with management of two patients with FH who presented to us in the second decade of life. Both patients required a coronary artery bypass grafting. The second patient underwent a patch aortoplasty for supra valvar aortic stenosis along with a coronary artery bypass.

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Long-term appraisal of coronary bypass operations in familial hypercholesterolemia

Cited by 13 publications

References 16 publications

Triple coronary artery bypass graft in a 10-year-old child with familial hypercholesterolemia

Triple coronary artery bypass graft in a 10-year-old child with familial hypercholesterolemia

Heterozygous Familial Hypercholesterolemia With APOE Haplotype: A Prospective Harbinger of a Catastrophic Cardiovascular Event

Coronary artery bypass surgery in the second decade of life

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