Long-term (8–10 years) outcomes after biodegradable polymer-coated biolimus-eluting stent implantation

Abstract

The long-term clinical outcomes after BP-BES implantation were favourable, although angiographic late progression of luminal narrowing did not reach a plateau. The incidence of ST remained notably low, whereas that of major bleeding gradually increased.

Five-Year Clinical Outcomes After XIENCE PRIME Everolimus Elution Coronary Stent System (EECSS) Implantation

“…Above all, these results demonstrated that the XIENCE PRIME EECSS has good safety in Chinese patients. Moreover, the incidence of new lesion revascularization was nearly double that of TLR, similarly to the results of a long-term observational study in Japan [18] but inconsistent with Stone et al's conclusion that the incidence of subsequent cardiovascular events is almost equal for culprit and non-culprit lesions [19], possibly because some patients with poly-vascular disease and diabetes were enrolled in the study. In addition, the cumulative rate of major bleeding events increased progressively and eventually reached a relatively low level of 4.4% at 5 years.…”

“…Moreover, 3.3% of patients had any MI at 5 years, a higher percentage than that in the Japanese Co-Cr EES study, whereas cardiac death was 2.2% lower than that in the Co-Cr EES (3.8%). Furthermore, other clinical endpoints including any TLR (6.7%) were also lower than observed in previous clinical research on biodegradable polymer-coated biolimus-eluting stents (16.3%) [18] and Co-Cr EES (7.2%) [14] in Japan. Above all, these results demonstrated that the XIENCE PRIME EECSS has good safety in Chinese patients.…”