Long sleep duration and cause‐specific mortality according to physical function and self‐rated health: the Ohsaki Cohort Study

Abstract

SummaryAlthough several studies have examined the association between sleep duration and all-cause or cause-specific mortality, it is unclear whether long sleep duration might merely reflect decreased physical strength and poorer health status. We therefore examined the association between sleep duration and all-cause and cause-specific mortality, and conducted stratified analysis based on physical function and self-rated health. This study used prospective data from the Ohsaki Cohort Study, conducted in Miyagi Prefecture, in northern Japan. This study population comprised 49 256 subjects aged 40-79 years at the baseline survey. We estimated hazard ratios (HRs) and 95% confidence intervals (CIs) of all-cause and cause-specific mortality according to the five categories of sleep duration (≤6, 7, 8, 9, ≥10 h day À1

Self‐Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose‐Response Meta‐Analysis

“…A total of 74 studies met the inclusion criteria; the process of study selection is shown in Figure 1 8, 9, 11, 12, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89,...…”

“…A total of 537, 47, 49, 75, 78 and 12*** studies were included in spline analysis for CHD mortality and CHD, respectively. Linear spline analysis failed to demonstrate any significant difference for both outcomes for self‐reported shorter and longer sleep durations (Figure 3, cubic model in Data S8).…”

“…For the meta‐analysis, there were 7 studies37, 47, 49, 51, 61, 75, 78 (Data S11) and 15 studies**** (Data S12) for CHD mortality and CHD, respectively. Although there were fewer studies, a similar J‐shaped pattern was observed where there was greater risk of CHD mortality and events with incremental deviation from the reference 7 to 8 hours of self‐reported sleep (a modest increase for 6 hours and greater increase for ≤5 hours; Data S10).…”

“…Linear spline analysis for stroke mortality and stroke included 347, 49, 65 and 98, 22, 31, 42, 43, 50, 69, 76, 83 studies, respectively. There was no difference in stroke events associated with self‐reported sleep duration shorter or longer than 7 hours, but a moderate increase in stroke mortality if sleep duration was >7 hours (Figure 3, Data S8).…”

“…Meta‐analysis of 5 studies27, 47, 49, 51, 65 were included in the analysis of stroke mortality (Data S10). For stroke events, there were 13 studies †.…”