Long period fiber grating based sensor for the detection of triacylglycerides

Baliyan, Anjli; Sital, Shivani; Tiwari, Umesh; Gupta, Rani; Sharma, Enakshi K.

doi:10.1016/j.bios.2015.12.089

Cited by 42 publications

(15 citation statements)

References 30 publications

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“…Baliyan et al [88], instead, presented a lipase enzyme-coated LPG for the detection of triacylglycerides in human blood. The authors showed the effect of pH on the sensor response, and the best performance, i.e., 0.5 mM, the lowest detectable concentration, was achieved at a temperature of 37 °C and pH of 7.4.…”

Section: Biosensorsmentioning

confidence: 99%

Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors

et al. 2017

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A metrological assessment of grating-based optical fiber sensors is proposed with the aim of providing an objective evaluation of the performance of this sensor category. Attention was focused on the most common parameters, used to describe the performance of both optical refractometers and biosensors, which encompassed sensitivity, with a distinction between volume or bulk sensitivity and surface sensitivity, resolution, response time, limit of detection, specificity (or selectivity), reusability (or regenerability) and some other parameters of generic interest, such as measurement uncertainty, accuracy, precision, stability, drift, repeatability and reproducibility. Clearly, the concepts discussed here can also be applied to any resonance-based sensor, thus providing the basis for an easier and direct performance comparison of a great number of sensors published in the literature up to now. In addition, common mistakes present in the literature made for the evaluation of sensor performance are highlighted, and lastly a uniform performance assessment is discussed and provided. Finally, some design strategies will be proposed to develop a grating-based optical fiber sensing scheme with improved performance.

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Section: Biosensorsmentioning

confidence: 99%

Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors

et al. 2017

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“…The cleaned fiber was coated with Ag-NPs by dip coating method, in which the fiber was dipped vertically into a long narrow cylindrical vessel containing the Ag-NPs solution. The Ag-NPs-coated fiber was dipped in 10% ethanolic solution of 3-APTES 19,23 for 2 min to create the amino functional group (−NH 2 ) on the surface of Ag-NPs. The functionalized fiber was then immersed into lipase enzyme solution made by dissolving typically 40 mg of lipase (Lip11) enzyme in 10 ml of PBS.…”

Section: Fabrication Of Sensing Probementioning

confidence: 99%

“…The presence of triacylglyceride molecules in the environment of the sensing region changes the refractive index and thickness of the biorecognition film due to the hydrolization of triacylglycerides by lipase enzyme. 19 As a consequence, the absorbance spectra of the metal nanoparticles change significantly. The characterization of the present sensing probe has been carried out using different concentrations of triacylglyceride solution ranging from 0 to 7 mM (which corresponds to 0 to 619.78 mg∕dl).…”

Section: Introductionmentioning

confidence: 99%

Localized surface plasmon resonance–based fiber-optic sensor for the detection of triacylglycerides using silver nanoparticles

et al. 2017

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A label-free technique for the detection of triacylglycerides by a localized surface plasmon resonance (LSPR)-based biosensor is demonstrated. An LSPR-based fiber-optic sensor probe is fabricated by immobilizing lipase enzyme on silver nanoparticles (Ag-NPs) coated on an unclad segment of a plastic clad optical fiber. The size and shape of nanoparticles were characterized by high-resolution transmission electron microscopy and UV-visible spectroscopy. The peak absorbance wavelength changes with concentration of triacylglycerides surrounding the sensor probe, and sensitivity is estimated from shift in the peak absorbance wavelength as a function of concentration. The fabricated sensor was characterized for the concentration of triacylglyceride solution in the range 0 to 7 mM. The sensor shows the best sensitivity at a temperature of 37°C and pH 7.4 of the triacylglycerides emulsion with a response time of 40 s. A sensitivity of 28.5 nm/mM of triacylglyceride solution is obtained with a limit of detection of 0.016 mM in the entire range of triacylglycerides. This compact biosensor shows good selectivity, stability, and reproducibility in the entire physiological range of triacylglycerides and is well-suited to real-time online monitoring and remote sensing.

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“…In chemosensing area, Yin et al presented a 3D patterning of poly(acrylic acid) ionic hydrogel decorated LPG pH Sensor [ 26 ]; Wang et al adopted LPG sensing approach to measure humidity [ 27 ]; Wang et al carried out an LPG sensor with nano-assembled porphyrin layers to detect the concentration of ammonia gas [ 28 ]; Hsu et al used a double notched LPG to sense CO 2 gas [ 29 ]; Baliyan et al proposed a lipid sensor using the LPG [ 30 ]; Celebanska et al and Tripathi et al had conducted their trials on the aptasensor using LPG for monitoring cocaine [ 31 ] and toxin [ 32 ], respectively.…”

Section: Introductionmentioning

confidence: 99%

Label-Free and Reproducible Chemical Sensor Using the Vertical-Fluid-Array Induced Optical Fiber Long Period Grating (VIOLIN)

Long

et al. 2020

Sensors

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Fiber optical refractometers have gained a substantial reputation in biological and chemical sensing domain regarding their label-free and remote-operation working mode. However, the practical breakthrough of the fiber optical bio/chemosensor is impeded by a lack of reconfigurability as well as the explicitness of the determination between bulk and surface refractive indices. In this letter, we further implement the highly flexible and reproducible long period grating called “VIOLIN” in chemical sensing area for the demonstration of moving those obstacles. In this configuration, the liquid is not only leveraged as the chemical carrier but also the periodic modulation of the optical fiber to facilitate the resonant signal. The thiol compound that is adsorbed by the fluidic substrate can be transduced to the pure alteration of the bulk refractive index of the liquid, which can be sensitively perceived by the resonant drift. Taking advantage of its freely dismantled feature, the VIOLIN sensor enables flexible reproduction and high throughput detection, yielding a new vision to the fiber optic biochemical sensing field.

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Long period fiber grating based sensor for the detection of triacylglycerides

Cited by 42 publications

References 30 publications

Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors

Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors

Localized surface plasmon resonance–based fiber-optic sensor for the detection of triacylglycerides using silver nanoparticles

Label-Free and Reproducible Chemical Sensor Using the Vertical-Fluid-Array Induced Optical Fiber Long Period Grating (VIOLIN)

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