Löfgren syndrome in Turkey

Abstract

In the 36-year period between 1966 and 2002, 514 patients were diagnosed with sarcoidosis at Cerrahpaşa Medical Faculty, Istanbul, Turkey, and of these 98 (19.1%) had Löfgren syndrome. The frequency of female patients with Löfgren was higher than the frequency among other sarcoidosis patients (female:male ratio 4.8 vs. 1.64; P < 0.001). Erythema nodosum was diagnosed in 72.4% of the subjects and arthritis or arthralgia was diagnosed in 51%. Erythema nodosum and arthritis or arthralgia were more frequent in Löfgren; however, pulmonary parenchymal involvement was more frequent in other sarcoidosis patients (all P-values < 0.001).

Sarcoidosis

“…Bilateral hiler lenfadenopati, ateş, artralji, eritema nodozum ve üveiti içerir. Bu klinik tabloyla başlayan sarkoidozun 2 yıl içinde yaklaşık %80 düzelme şansı vardır (21).…”

Sarcoidosis with Acute Recurrent Polyarthritis and Hypercalcemia

“…The onset of arthritis is acute or chronic. Acute sarcoid arthritis typically occurs in the lower extremities, and is often associated with bilateral hilar lymphadenopathy (BHL) and erythema nodosum (EN) (4). Acute sarcoidosis with the triad of acute arthritis, BHL, and EN was described as Löfgren's syndrome (5 F i g u r e 1 .…”