2019
DOI: 10.3390/s19214614
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Lock-in Amplifier-Based Impedance Detection of Tissue Type Using a Monopolar Injection Needle

Abstract: For successful intra-articular injection therapy, it is essential to accurately position the tip of the injection needle into the target joint area while administering the drug into the affected tissue. In this study, we investigated the feasibility of a monopolar injection needle and lock-in amplifier (LIA)-based impedance measurement system for detecting the tissue type where the needle tip is located. After positioning the monopolar injection needle tip into the dermis, hypodermis, or muscle layer of pork t… Show more

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Cited by 7 publications
(6 citation statements)
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“…In fact, there may be systematic errors in the measurement [100]. Kim positioned the monopolar injection needle to the dermis, subcutaneous tissue, or muscle layer of pork tissue, and then measured electrical impedance in the frequency range of 10 Hz to 10 kHz based on an impedance analyzer [101]. This method has also been proven to be used for pork quality monitoring.…”
Section: Food Quality Inspectionmentioning
confidence: 99%
“…In fact, there may be systematic errors in the measurement [100]. Kim positioned the monopolar injection needle to the dermis, subcutaneous tissue, or muscle layer of pork tissue, and then measured electrical impedance in the frequency range of 10 Hz to 10 kHz based on an impedance analyzer [101]. This method has also been proven to be used for pork quality monitoring.…”
Section: Food Quality Inspectionmentioning
confidence: 99%
“…A monopolar needle was used to simultaneously measure the impedance and administer the drug. Electrical impedance monitoring revealed major differences between the dermis, hypodermis, and muscle tissue [23,24].…”
Section: Introductionmentioning
confidence: 99%
“…In homogeneous volumes, such as biological tissue, monopolar and bipolar electrical impedance setups have very similar operations [ 22 ]. Earlier studies showed that the monopolar needle was preferable for intra-articular infusion treatment, as it is simple to use, inexpensive, easily available on the market and no semiconductor technique is required [ 23 , 24 ].…”
Section: Introductionmentioning
confidence: 99%
“…Since with the CRs, the frequency dependence of impedance standards with traceability to the QHR can be measured, they are used as references for high-accuracy electrical measurement systems [7][8][9]. Applications with medical and technologic impact involve high-accuracy impedance measurements, such as electrical characterization of tissue [10,11], cell detection [12], supercapacitors developments [13], impedance matching in wireless power transfer systems [14], voltage-controlled inverters for electrical grids [15], and characterization of lead-acid batteries [16,17], only to cite a few examples. To ensure the certainty of the results of environmental research, like solar cell characterization [18], toxicity measurements of nanoparticles [19], or Nitrogen fertilizer monitoring in plants [20], the traceability to fundamental constants of their impedance measurements needs to be fulfilled.…”
Section: Introductionmentioning
confidence: 99%