Locally Delivered Minocycline and Guided Tissue Regeneration to Treat Post‐Juvenile Periodontitis. A Case Report

Abstract

A case of post‐juvenile periodontitis in a 28‐year‐old female patient is described along with new periodontal treatment modalities. Administration of minocycline‐HCl with local drug delivery system was introduced as a part of initial periodontal therapy following microbiological and immunological examinations. The lesions were subsequently treated by guided tissue regeneration, which resulted in considerable gain of attachment with minimal recession of marginal gingiva. This observation suggests that the local delivery of antibiotics and regenerative therapy may prove to be effective alternative modalities in treatment of post‐juvenile periodontitis. J Periodontol 1994; 65:835–839.

Effect of a controlled release device containing minocycline microspheres on the treatment of chronic periodontitis: A comparative study

“…These findings are in consistent with the those of the earlier studies done by Vansteenberghe et al .,[10] Mullur et al .,[11] Saito et al .,[12] Jones et al .,[13] Timmerman et al .,[14] Hagiwara et al .,[15] and Vansteenberghe et al . [16]…”

“…Thus, when the gingival status was compared between Group A and Group B, a significant improvement was observed on day 30, day 90, and day 180 in the test sites [Graph 2]. This is consistent with the findings of the studies conducted by Muller et al .,[17] Vansteenberghe et al .,[10] Saito et al .,[12] Jones et al .,[13] Timmerman et al .,[14] Radvar et al ,[18] Hagiwara et al .,[15] Vansteenberghe et al .,[16] and Kinane et al . [19]…”

Treatment of Intrabony Periodontal Defects with Enamel Matrix Derivative in Private Practice: A Long-term Retrospective Study

“…The evaluation of subgingival microflora was not performed in the subjects of the present study, mainly due to the cost involved. A previous report by our group suggested the efficacy of local drug delivery of minocycline-HCl as an adjunctive modality in periodontal regeneration 19) . The effect of antimicrobial agents with EMD treatment is another area that needs to be investigated.…”

Generalized Aggressive Periodontitis and Its Treatment Options: Case Reports and Review of the Literature

“…Adjunctive use of LDD agents like controlled release biodegradable chlorhexidine gluconate chip [61, 62], tetracycline fibers [63, 64], and minocycline-Hcl gel [65] has been tried in aggressive periodontitis with superior clinical outcomes. The decision to use local anti-infective adjunctive therapy remains a matter of individual clinical judgment, the phase of treatment, and the patient's status and preferences.…”