Localized nasopharyngeal amyloidosis

Abstract

Localized amyloidosis, however rare, should be considered as differential diagnosis in any case of nasal obstruction with tubal dysfunction, even if bilateral. ENT physicians need to recognize and understand this pathology for adapted diagnostic and treatment planning.

Intensity-modulated radiotherapy for localized nasopharyngeal amyloidosis

“…Only 3 % of the cases occur in the nasopharyngeal region [9][10][11]. Patients with nasopharyngeal amyloidosis mainly complain about nasal obstruction, recurrent epistaxis, postnasal discharge, and hearing problems [12]. Amyloidosis is conclusively diagnosed by tissue biopsy.…”

A Rare Nasopharyngeal Presentation of Amyloidosis

“…11,12 Patients with nasopharyngeal amyloidosis mainly complain of nasal obstruction, epistaxis, posterior rhinorrhea, and hearing impairment. 13 Endoscopy generally shows an irregular, heterogeneously yellowish, smooth bulging mass. 14 On CT scan, these lesions usually appear as a well-defined, homogenous, smooth soft tissue mass without evidence of bony erosion.…”

Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge

“…Primary nasopharyngeal amyloidosis is a rare benign tumour in the head and neck region where the usual clinical presentation includes nasal obstruction, rhinorrhoea, epistaxis and reduced hearing [5] , [6] , [7] , all of which can mimic symptoms of other nasal diseases.…”