Localized lymphomatoid papulosis

González‐López, Marcos A.; González-Vela, María del Carmen; Caballero, Clara I.; Consuegra, Germana; Fernández‐Llaca, Héctor; Piris, Miguel Á.

doi:10.1111/ijd.12719

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…Unlike PALP, localized LyP may remit spontaneously [8]; however, some treatments have been used with variable results. These include topical and intralesional steroids, injections of γ-interferon, radiation therapy, minocycline, oral methotrexate, and phototherapy [9]. It is well known that patients with classic LyP have an increased risk of developing lymphoma; however, this relation is not so clear with localized LyP.…”

Section: Discussionmentioning

confidence: 99%

Papular eruption characteristic of persistent agmination of lymphomatoid papulosis

Martinez-de-Espronceda

Oscoz

et al. 2020

J Hematopathol

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A 48-year-old man presented with a 1-year history of a nontender, pruritic, well-circumscribed crop of waxing and waning papules. The histological findings were compatible with lymphomatoid papulosis (LyP) in spite of the fact that cutaneous distribution was not typical. Attending to the clinicopathological correlation, we established the diagnosis of persistent agmination of lymphomatoid papulosis (PALP). PALP is a rare variant of CD30+ primary cutaneous T cell lymphoproliferative disorder, with only a few reported cases in the literature. It is still controversial whether PALP is a subtype of localized LyP or an own entity. In any case, there is potential of developing malignancy, so at least a cautious long-term follow-up is recommended in these patients.

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Section: Discussionmentioning

confidence: 99%

Papular eruption characteristic of persistent agmination of lymphomatoid papulosis

Martinez-de-Espronceda

Oscoz

et al. 2020

J Hematopathol

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Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis

Stoll

Willner

et al. 2021

Journal of the American Academy of Dermatology

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Lymphomatoid papulosis: an update and review

Martínez-Cabriales

Walsh

Sade

et al. 2019

Acad Dermatol Venereol

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Lymphomatoid papulosis (LyP) is a benign chronic often relapsing skin condition that belongs to the CD30‐positive cutaneous lymphoproliferative disorders. LyP typically presents as crops of lesions with a tendency to self‐resolve, and morphology can range from solitary to agminated or diffuse papules and plaques to nodules or tumours. The clinical–histological spectrum can range from borderline cases to overlap with primary cutaneous anaplastic cell lymphoma (pcALCL). Histology and immunophenotype commonly show overlap with other CD30‐positive disorders and sometimes may be identical to pcALCL, making its diagnosis more difficult. Patients with LyP have an increased risk of developing a second neoplasm such as mycosis fungoides, pcALCL and/or Hodgkin lymphoma. Clinical correlation allows its proper classification and diagnosis, which is fundamental for treatment and prognosis. This review focuses on the clinical appearance, histopathological features, diagnosis, differential diagnosis and management of LyP.

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Localized lymphomatoid papulosis

Cited by 3 publications

References 10 publications

Papular eruption characteristic of persistent agmination of lymphomatoid papulosis

Papular eruption characteristic of persistent agmination of lymphomatoid papulosis

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis

Lymphomatoid papulosis: an update and review

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