Localized flushing absence after abobotulinum toxin A cosmetic treatment

Almeida, Hiram de; Henkin, Caroline Schwartz; Milman, Laura de Mattos; Bernardotti, Igor de Souza

doi:10.1684/ejd.2013.2134

Cited by 2 publications

(1 citation statement)

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“…Only few cases of these reactions have been reported in literature. [2][3][4] However, BTX has been used for treatment of conditions related to vasodilation and flushing for quite a long time. Numerous articles have been published confirming its efficacy for treatment of the Frey's syndrome, 5 rosacea, 6 menopausal 7 and heat stress [8][9][10] flushings and Harlequin syndrome.…”

Section: Discussionmentioning

confidence: 99%

Facial Blanching: An Unusual Side Effect after Botulinum Toxin Injection

Sharova¹

2018

JDC

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Background: Botulinum toxin (BTX) is widely used in different areas of medicine for treatment of neurological disorders related to muscle hypertonicity and spasticity. However, the results of studies conducted over the past decade suggest that the BTX molecule exerts more complex and diverse effects on the human body, including antinociceptive effect and vascular tone regulation. Main observations: We report case of a 37-year-old healthy Caucasian woman who complained of pale patches on her forehead 5 days after she had been injected with abobotulinumtoxin A. Previously the patient did not receive any BTX injections. Pale patches corresponded to the BTX injection sites and became visible against hyperemic background following intense physical activity. Conclusion: The adverse effect of BTX used for aesthetic indications in the form of facial blanshing at the injections sites is a rare manifestation of individual peculiarities of certain patients.

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