Localization of steroid hormone receptors in the apocrine sweat glands of the human axilla

Beier, Konstantin; Ginez, Isabelle; Schaller, Heidi

doi:10.1007/s00418-004-0736-3

Cited by 46 publications

(35 citation statements)

References 26 publications

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“…The estrogen receptor belongs to the steroid hormone nuclear receptor superfamily [23] , and it plays important roles on either regulation of various functions in skin, mainly hair growth, regulate sebaceous and sweat gland activity [24] or secretion of sexual pheromones [25] . Especially, apocrine sweat glands regarded as pheromone-producing scent glands [24] and their secretions play a role in demarcation of territorial area [6] .…”

Section: Discussionmentioning

confidence: 99%

“…Especially, apocrine sweat glands regarded as pheromone-producing scent glands [24] and their secretions play a role in demarcation of territorial area [6] . The interdigital sinus is a structure which is rich in apocrine glands.…”

Section: Discussionmentioning

confidence: 99%

“…The immunoreaction of estrogen receptor was stronger in apocrine sweat glands. Estrogen receptor was observed in human skin and it was reported that there were immunoreaction of estrogen receptor in epidermis, sweat and sebaceous glands [24,26] . Our findings are consistent with these reports.…”

Section: Discussionmentioning

confidence: 99%

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Kıvırcık Koyunlarda Sinus Interdigitalis’in Morfolojik ve Immunohistokimyasal Özellikleri

Suzer¹,

AKKOÇ²,

Arican³

et al. 2015

Kafkas Univ Vet Fak Derg

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Interdigital sinus secretions play a role in sexual behavior and reproductive process of sheep. In the present study, it was aimed to characterize the topographical, anatomical and immunohistological features of interdigital sinus in Kivircik sheep. The interdigital sinuses were dissected from 50 forefeet of female Kivircik sheep which were slaughtered in the slaughterhouse. The shape of sinus resembled a pipe and was located between the proximal and distal interphalangeal joints of two digits. The wall of interdigital sinus had three layers as epidermis, dermis and fibrous capsule. Epidermis consisted of a stratified squamous keratinized epithelium. Sebaceous glands, hair follicles, arrector pili muscles, and apocrine sweat glands were in the dermis. Furthermore, there were vessels and adipose tissue in the fibrous capsule. There was immunohistochemical reaction for estrogen receptor expressed in epidermis, apocrin sweat glands and sebaceous glands of interdigital sinus. In conclusion, our results about the topographical, anatomical and immunohistological features of interdigital sinus are very important to understand sexual behavior and reproductive process of sheep, and to make a new approach for its surgery. Furthermore, this study is the first to report the interdigital sinus of Kivircik sheep immunohistochemically. Keywords: Interdigital sinus, Kivircik sheep, Morphology, Immunohistochemistry Kıvırcık Koyunlarda Sinus Interdigitalis'in Morfolojik veImmunohistokimyasal Özellikleri ÖzetSinus interdigitalis salgıları koyunlarda seksüel davranış ve üreme sürecinde rol oynamaktadır. Bu çalışma ile Kıvırcık koyunlarda sinus interdigitalis'in, topografik, anatomik ve immünohistolojik özelliklerinin tanımlanması amaçlanmıştır. Çalışmada kullanılan sinus interdigitalis 'ler, mezbahada kesilen 50 adet Kıvırcık koyunun ön ayaklarından disseke edildi. Şekli bir pipoyu andıran sinus interdigitalis'in, iki parmak arasında articulatio interphalangea proksimalis ve distalis manus hizasında yerleştiği gözlendi. Sinus interdigitalis duvarının epidermis, dermis ve fibröz kapsül olarak üç katmandan oluştuğu gözlendi. Epidermis'in, çok katlı yassı keratinize epitelden oluştuğu saptanırken, dermis katmanında yağ bezleri, kıl folikülleri, mm. arrectores pilorum ve apokrin ter bezlerinin varlığı görüldü. Ayrıca, fibröz kapsül içerisinde kapillar damarlar ve yağ doku bulunmaktaydı. Sinus 'un epidermis, apokrin ter bezleri ve yağ bezlerinde östrojen reseptörleri için immünhistokimyasal tepki olduğu gözlendi. Sonuç olarak, sinus interdigitalis'in topografik, anatomik ve immünohistolojik özellikleri hakkında elde ettiğimiz sonuçlar, koyunlardaki seksüel davranış ve üreme sürecini anlama ve sinus interdigitalis'in operasyonlarına yeni bir yaklaşım geliştirmesi bakımından önemlidir. Çalışma, Kıvırcık koyunlarda sinus interdigitalis'in immunohistokimyasal yapısı üzerine yapılan ilk çalışmadır.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Kıvırcık Koyunlarda Sinus Interdigitalis’in Morfolojik ve Immunohistokimyasal Özellikleri

Suzer¹,

AKKOÇ²,

Arican³

et al. 2015

Kafkas Univ Vet Fak Derg

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“…Beier et al (2005) by localizing immunohistochemically the AR and estrogen receptors (ER and ER ) in the apocrine glands found evidence for a correlation between steroid-receptor expression and induction of secretory activity for pheromones.…”

Section: Hormone Cell Biologymentioning

confidence: 99%

The histochemistry and cell biology vade mecum: a review of 2005–2006

Taatjes

Zuber

Roth

2006

Histochem Cell Biol

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The procurement of new knowledge and understanding in the ever expanding discipline of cell biology continues to advance at a breakneck pace. The progress in discerning the physiology of cells and tissues in health and disease has been driven to a large extent by the continued development of new probes and imaging techniques. The recent introduction of semi-conductor quantum dots as stable, specific markers for both fluorescence light microscopy and electron microscopy, as well as a virtual treasure-trove of new fluorescent proteins, has in conjunction with newly introduced spectral imaging systems, opened vistas into the seemingly unlimited possibilities for experimental design. Although it oftentimes proves difficult to predict what the future will hold with respect to advances in disciplines such as cell biology and histochemistry, it is facile to look back on what has already occurred. In this spirit, this review will highlight some advancements made in these areas in the past 2 years.

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“…Beier et al (2005) have localized by immunohistochemistry the androgen receptor (AR) and estrogen receptors (ERalpha and ERbeta) in the apocrine glands. They found strong nuclear immunoreactivity for AR and ERbeta in the secretory epithelium.…”

Section: Hormones: Cellular Origin and Cellular Effectsmentioning

confidence: 99%

Recent progress in histochemistry and cell biology: the state of the art 2005

Taatjes

Roth

2005

Histochem Cell Biol

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Advances in the field of histochemistry, a multidisciplinary area including the detection, localization and functional characterization of molecules in single cells and complex tissues, often drives the attainment of new knowledge in the broadly defined discipline of cell biology. These two disciplines, histochemistry and cell biology, have been joined in this journal to facilitate the flow of information with celerity from technical advancement in histochemical procedures, to their utilization in experimental models. This review summarizes advancements in these fields during the past year.

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Localization of steroid hormone receptors in the apocrine sweat glands of the human axilla

Cited by 46 publications

References 26 publications

Kıvırcık Koyunlarda Sinus Interdigitalis’in Morfolojik ve Immunohistokimyasal Özellikleri

Kıvırcık Koyunlarda Sinus Interdigitalis’in Morfolojik ve Immunohistokimyasal Özellikleri

The histochemistry and cell biology vade mecum: a review of 2005–2006

Recent progress in histochemistry and cell biology: the state of the art 2005

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