Local neural block at the wrist for treatment of palmar hyperhidrosis with botulinum toxin: Technical improvements

Campanati, Anna; Lagalla, G.; Penna, Luca; Gesuita, Rosaria; Offidani, Annamaria

doi:10.1016/j.jaad.2003.09.006

Cited by 33 publications

(16 citation statements)

References 20 publications

(58 reference statements)

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“…Proper use of anesthesia is vital to the success of BTX‐A in the treatment of palmar hyperhidrosis due to the intense pain associated with multiple injections into the palms. Bier's block, nerve blocks, application of ice or cold air before and after injection, and vibration have all been shown to be successful in reducing pain during treatment 73–78 . Proper counseling on the potential side effects of anesthesia should inform the patient of possible damage to peripheral nerves and vessels.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have been performed examining the efficacy and safety of BTX-A in the treatment of palmar hyperhidrosis. [56][57][58][59][60][61][62][63][64][65][66] Duration of euhidrosis by and large exceeded the length of the study and response rate was consistently above 90%. The most noteworthy adverse event was transient weakness of the intrinsic hand muscles, for which patients should be counseled regarding dangers of poor fine motor control.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Comprehensive Approach to the Recognition, Diagnosis, and Severity-Based Treatment of Focal Hyperhidrosis: Recommendations of the Canadian Hyperhidrosis Advisory Committee

Solish

Bertucci

Dansereau³

et al. 2007

Dermatol Surg

266

390

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Comprehensive Approach to the Recognition, Diagnosis, and Severity-Based Treatment of Focal Hyperhidrosis: Recommendations of the Canadian Hyperhidrosis Advisory Committee

Solish

Bertucci

Dansereau³

et al. 2007

Dermatol Surg

266

390

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show abstract

“…Attempts to reduce injection-related pain have included topical anesthetics (e.g. lidocaine [lignocaine] [155] or tetracaine [158] ); cryoanalgesia with ice, [159] cold air, [148] or dichlorotetrafluoroethane; [160,161] regional nerve blocks; [162][163][164][165] intravenous regional anesthesia (IVRA; Bier's block); [166,167] needle-free injection (e.g. MED-JET Ò ); [157,168] and vibration anesthesia.…”

Section: Palmar Hhmentioning

confidence: 99%

Botulinum Toxin for Hyperhidrosis

Grunfeld

Murray

Solish

2009

American Journal of Clinical Dermatology

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Primary focal hyperhidrosis is a disorder of idiopathic excessive sweating that typically affects the axillae, palms, soles, and face. The disorder, which affects up to 2.8% of the US population, is associated with considerable physical, psychosocial, and occupational impairments. Current therapeutic strategies include topical aluminum salts, tap-water iontophoresis, oral anticholinergic agents, local surgical approaches, and sympathectomies. These treatments, however, have been limited by a relatively high incidence of adverse effects and complications. Non-surgical treatment complications are typically transient, whereas those of surgical therapies may be permanent and significant. Recently, considerable evidence suggests that botulinum toxin type A (BTX-A) injections into hyperhidrotic areas can considerably reduce focal sweating in multiple areas without major adverse effects. BTX-A has therefore shown promise as a potential replacement for more invasive treatments after topical aluminum salts have failed. This article reviews the epidemiology, diagnosis, and management of primary focal hyperhidrosis, with an emphasis on recent research evidence supporting the use of BTX-A injections for this indication.

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“…Palmar hyperhidrosis requires higher doses (120U–220U BOTOX ® ) due to larger surface area, and a greater number of injections (Naumann and Jost 2004). Adverse effects can include considerable pain necessitating local anesthesia (Benohanian 2007) or nerve block (Campanati et al 2004) and intrinsic hand muscle weakness. Topical use of botulinum toxin has been suggested for hyperhidrosis as well (Lim et al 2006).…”

Section: Botulinum Toxin a In Clinical Neurologymentioning

confidence: 99%

Neurologic uses of botulinum neurotoxin type A

Ney

Joseph²

2008

NDT

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Abstract:This article reviews the current and most neurologic uses of botulinum neurotoxin type A (BoNT-A), beginning with relevant historical data, neurochemical mechanism at the neuromuscular junction. Current commercial preparations of BoNT-A are reviewed, as are immunologic issues relating to secondary failure of BoNT-A therapy. Clinical uses are summarized with an emphasis on controlled clinical trials (as appropriate), including facial movement disorders, focal neck and limb dystonias, spasticity, hypersecretory syndromes, and pain.

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Local neural block at the wrist for treatment of palmar hyperhidrosis with botulinum toxin: Technical improvements

Cited by 33 publications

References 20 publications

A Comprehensive Approach to the Recognition, Diagnosis, and Severity-Based Treatment of Focal Hyperhidrosis: Recommendations of the Canadian Hyperhidrosis Advisory Committee

A Comprehensive Approach to the Recognition, Diagnosis, and Severity-Based Treatment of Focal Hyperhidrosis: Recommendations of the Canadian Hyperhidrosis Advisory Committee

Botulinum Toxin for Hyperhidrosis

Neurologic uses of botulinum neurotoxin type A

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