Local DNA microviscosity converts ruthenium polypyridyl complexes to ultrasensitive photosensitizers

Quantitative Determination of Endoplasmic Reticulum Viscosity during Immunogenic Cell Death by a Theranostic Rhenium Complex

“…Phosphorescent metal complexes are characterized by their instinct photophysical and photochemical properties that can be utilized to construct photodynamic anticancer agents or imaging agents . Moreover, we and other groups have shown that by integrating the imaging and therapeutic properties in a single molecule, these emissive complexes can be applied as novel theranostic agents. − …”

Trivalent metal ion sensor enabled bioimaging and quantification of vaccine-deposited Al3+in lysosomes

“…Judiciously, we grafted the well-known lysosome-targeting morpholine (Mor) moiety to the 2′,4′-dihydroxyacetophenone core and nucleophilically substituted it to the ring-closed rhodamine, forming the third chemosensor: Rh-A-Mor. All the synthesized molecules were comprehensively characterized by 1 H and 13 C NMR and high-resolution mass spectrometry (HRMS) (Fig. S1-S13, ESI †).…”

“…The pile-up of inessential aluminium hampers the central nervous system, leading to neurodegenerative disorders such as Parkinson's and Alzheimer's. 2,[11][12][13] Surprisingly, the massive burden of Al 3+ on mankind is primarily due to vaccination because 75% of adjuvant-based treatments utilize aluminium salts as adjuvants. 14 For instance, aluminium hydroxides and phosphates are implemented in veterinary vaccinology for adsorbing the vaccine antigens to formulate medication for hepatitis A and B, Streptococcus pneumonia, diphtheria, pertussis-tetanus, and human papilloma.…”

Controlled assembly of photosensitizers through directional interactions for effective photooxidation

“…S8a, ESI †), indicating that the aggregations of 2 were easy to react with oxygen. [30][31][32] In great contrast to interdigitated 1, the absorption maximum of 2 in mixed solution (Fig. 3b) is red-shifted with respect to the molecularly dissolved state on heating, indicating the formation of J-type aggregates in the self-assembly of 2 (Fig.…”