Local Anesthesia Obtained via Iontophoresis as an Aid to Shave Biopsy

Jm, Maloney

doi:10.1001/archderm.1992.01680130045004

Cited by 22 publications

(5 citation statements)

References 3 publications

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“…Lidocaine iontophoresis provides anesthesia more rapidly than EMLA 10,11 and may be preferable for deeper procedures, as EMLA cream provides anesthesia to a depth of 5 mm in an hour, whereas lidocaine iontophoresis provides anesthesia of greater than 8 mm in 10 minutes 17–29 . In a comparative trial of EMLA and lidocaine iontophoresis before venous cannulation in pediatric subjects, lidocaine iontophoresis was significantly more effective in reducing the pain associated with the procedure 17 .…”

Section: Discussionmentioning

confidence: 99%

“…Lidocaine delivered iontophoretically is effective for reduction of the pain associated with venous cannulation in pediatric and adult patients and provides better pain relief than EMLA in this setting 15–19 . Previous studies of iontophoresis for dermatologic procedures have been limited to a small number of patients and performed in uncontrolled settings 20–25 . To better assess its efficacy and safety, we performed a randomized, double‐blinded comparison of lidocaine iontophoresis to placebo for topical anesthesia before shave biopsy.…”

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confidence: 99%

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Lidocaine Iontophoresis for Local Anesthesia Before Shave Biopsy

Zempsky

Parkinson

2003

Dermatol Surg

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Lidocaine Iontophoresis for Local Anesthesia Before Shave Biopsy

Zempsky

Parkinson

2003

Dermatol Surg

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“…Lidocaine iontophoresis has been shown to be effective in reducing the pain associated with venous cannulation in pediatric and adult patients, and to be superior to EMLA in a comparative trial (13–16). While its efficacy has been shown for topical anesthesia prior to dermatologic procedures, these studies have suffered from small sample size, lack of randomization or blinding, and failure to include an appropriate pediatric sample (17–22). We performed a randomized, double‐blind comparison of lidocaine iontophoresis to placebo for topical anesthesia prior to routine dermatologic procedures in children.…”

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confidence: 99%

Lidocaine Iontophoresis for Topical Anesthesia Before Dermatologic Procedures in Children: A Randomized Controlled Trial

Wagner¹,

Cunningham²,

Zempsky

et al. 2003

Pediatric Dermatology

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Local anesthesia by injection in pediatric patients undergoing dermatologic procedures is not well received because of the pain of injection and the fear of needles. Lidocaine iontophoresis is a method of topical anesthesia where lidocaine is driven into the skin under the influence of electric current. We performed a prospective double-blind, placebo-controlled evaluation of iontophoresis of 2% lidocaine with 1:100,000 epinephrine. Sixty children requiring dermatologic procedures were enrolled (50 shave biopsy, 7 curettage, 2 injection, 1 punch biopsy). Twenty-nine of 31 patients in the lidocaine group versus 2 of 29 placebo patients required no supplemental anesthesia (p < 0.001). The pain reported by the patients on the Oucher pain scale subsequent to the procedure was significantly lower in the lidocaine group (p < 0.001). Investigators and parents also rated pain lower in the lidocaine group (p < 0.001). Blanching and/or erythema occurred in 58 of 60 patients, but resolved within 1 hour in all patients. There were no other adverse events. Lidocaine iontophoresis is a safe and effective method of topical anesthesia prior to dermatologic procedures in children.

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“…It is a hydrochloride salt that dissociates into a positively charged molecule. Iontophoresed lidocaine can lead to significant anesthesia to a depth of at least several millimeters 13–18 …”

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Iontophoresis as a Tool for Anesthesia in Dermatologic Surgery: An Overview

Greenbaum

2001

Dermatol Surg

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One of the biggest challenges of performing dermatologic surgery procedures is to minimize pain. Not only will the experience of each patient be enhanced by increased comfort, but the medical and aesthetic results achieved by the physician will be facilitated as well. Iontophoresis is the use of electrical impulses to drive molecules into the skin. Anesthetic agents are one type of medicine that can be delivered in such a way. There is a tremendous potential for the applications of iontophoresis to be expanded. As our understanding of the technique increases we will be able to modify the skin's surface as well as the individual agents we wish to transport.

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Local Anesthesia Obtained via Iontophoresis as an Aid to Shave Biopsy

Cited by 22 publications

References 3 publications

Lidocaine Iontophoresis for Local Anesthesia Before Shave Biopsy

Lidocaine Iontophoresis for Local Anesthesia Before Shave Biopsy

Lidocaine Iontophoresis for Topical Anesthesia Before Dermatologic Procedures in Children: A Randomized Controlled Trial

Iontophoresis as a Tool for Anesthesia in Dermatologic Surgery: An Overview

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