Lobectomy Combined With Volume Reduction For Patients With Lung Cancer And Advanced Emphysema

DeMeester, Steven R.; Patterson, G. Alexander; Sundaresan, R. Sudhir; Cooper, Joel D.

doi:10.1016/s0022-5223(98)70334-4

Cited by 57 publications

(16 citation statements)

References 19 publications

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“…However, multiple case series suggest that patients with extremely poor lung function can tolerate combined LVRS and resection of the lung cancer with an acceptable mortality rate and surprisingly good postoperative outcomes. 106,[217][218][219][220][221][222][223][224][225] Others have also described curative-intent surgical resections among patients with LVRS and have found signifi cant and lasting improvements in FEV 1 . 224,225 per se, planned ambulation within 4 h following a resection has been associated with improved oxygenation and lower external oxygen requirements.…”

Section: Lung Volume Reduction Surgerymentioning

confidence: 99%

Physiologic Evaluation of the Patient With Lung Cancer Being Considered for Resectional Surgery

Brunelli

Kim

Berger

et al. 2013

Chest

734

448

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Section: Lung Volume Reduction Surgerymentioning

confidence: 99%

Physiologic Evaluation of the Patient With Lung Cancer Being Considered for Resectional Surgery

Brunelli

Kim

Berger

et al. 2013

Chest

734

448

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“…A subgroup of patients with upper lobe emphysema appeared to be the ideal candidates, LVRS producing significant improvement in exercise capacity with better survival [210,211]. Several case series and post hoc analysis of hospital registries have indicated acceptable operative death rate and cardiopulmonary morbidity following LVRS in patients with solitary nodules and extremely poor lung function [212][213][214][215][216][217][218].…”

Section: Surgical Techniques In Lung Cancermentioning

confidence: 99%

ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)

Brunelli¹,

Charloux²,

Bolliger³

et al. 2009

Eur Respir J

757

550

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A collaboration of multidisciplinary experts on the functional evaluation of lung cancer patients has been facilitated by the European Respiratory Society (ERS) and the European Society of Thoracic Surgery (ESTS), in order to draw up recommendations and provide clinicians with clear, up-to-date guidelines on fitness for surgery and chemo-radiotherapy.The subject was divided into different topics, which were then assigned to at least two experts. The authors searched the literature according to their own strategies, with no central literature review being performed. The draft reports written by the experts on each topic were reviewed, discussed and voted on by the entire expert panel. The evidence supporting each recommendation was summarised, and graded as described by the Scottish Intercollegiate Guidelines Network Grading Review Group. Clinical practice guidelines were generated and finalised in a functional algorithm for risk stratification of the lung resection candidates, emphasising cardiological evaluation, forced expiratory volume in 1 s, systematic carbon monoxide lung diffusion capacity and exercise testing.Contrary to lung resection, for which the scientific evidences are more robust, we were unable to recommend any specific test, cut-off value, or algorithm before chemo-radiotherapy due to the lack of data. We recommend that lung cancer patients should be managed in specialised settings by multidisciplinary teams.

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“…Among 8 patients who have undergone anatomical resections, 6 underwent lobectomy and, in 2 of these, a tangential resection of the pulmonary artery was performed to avoid a pneumonectomy. Satisfactory improvements in respiratory function measures, exercise capacity, and subjective dyspnea had already been reported after lobectomy for NSCLC in emphysema patients by De Meester and colleagues [9] and by Edwards and colleagues [10] while no data existed so far on HRQOL changes. In a recent series on LVR [7], lobectomies were carried out in patients with a severely emphysematous target lobe but contralateral LVR was always added.…”

Section: Commentmentioning

confidence: 94%

Quality of life after tailored combined surgery for stage I non–small-cell lung cancer and severe emphysema

Pompeo

Dominicis

Ambrogi

et al. 2003

The Annals of Thoracic Surgery

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Background. We analyzed the early and long-term quality of life changes occurring in 16 patients undergoing tailored combined surgery for stage I non-small-cell lung cancer (NSCLC) and severe emphysema.Methods. Mean age was 65 ؎ 5 years. All patients had severe emphysema with severely impaired respiratory function and quality of life. Tumor resection was performed with sole lung volume reduction (LVR) in 5 patients, separate wedge resection in 3 patients, segmentectomy in 2 patients, and lobectomy in 6 patients. A bilateral LVR was performed in 5 patients. Quality of life was assessed at baseline and every 6 months postoperatively by the Short-form 36 (SF-36) item questionnaire.Results. Mean follow-up was 44 ؎ 21 months. All tumors were pathologic stage I. There was no hospital mortality nor major morbidity. Significant improvements

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Lobectomy Combined With Volume Reduction For Patients With Lung Cancer And Advanced Emphysema

Cited by 57 publications

References 19 publications

Physiologic Evaluation of the Patient With Lung Cancer Being Considered for Resectional Surgery

Physiologic Evaluation of the Patient With Lung Cancer Being Considered for Resectional Surgery

ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)

Quality of life after tailored combined surgery for stage I non–small-cell lung cancer and severe emphysema

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